FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2188765627> ?p ?o ?g. }

• W2188765627 abstract "We are interested in cellular co-expression patterns of a-amino-3-hydroxy-5-methyl-4-isoxazole-propionate (AMPA) receptor subunits 1–4 (GluR1–4) in substance P receptor (SPR)-containing neurons of the basal forebrain, which may act as a morphological basis for interaction between neurokinins and glutamate-driven neuronal signaling and excitotoxicity. Immunohistochemistry and laser scanning confocal microscopy in adult C57/BL mice revealed that distribution of SPR-positive neurons overlapped with that of GluR1–4-containing ones in most basal forebrain regions, i.e. the medial septal nucleus, nucleus of diagonal band of Broca, magnocellular preoptic nucleus and substantia innominata. Neurons showing both SPR and GluR1–4-immunoreactivities were found in above cholinergic neurons-rich containing basal forebrain regions. Semiquantification analysis indicated that about 57–95% of SPR-positive neurons displayed GluR1–4-immunoreactivity. The percentages of AMPA receptor subunits co-localizing in SPR-positive neurons were GluR4 (48%), GluR1 (47%), GluR2 (26%) and GluR3 (20%), respectively. However, the neurons co-expressing SPR and GluR1–4 were hardly detected in the basal nucleus of Meynert of the basal forebrain. The co-localization of SPR and AMPA receptors has provided a molecular basis for functional interaction between neurokinins and AMPA receptors-mediated signaling in basal forebrain neurons. This study has also implied that glutamate-driven neuronal transmission and excitotoxicity can be modulated by neurokinin peptides in most basal forebrain regions but not in the basal nucleus of Meynert, suggesting that neurokinins or SP may play certain roles in determining neuronal functional properties or excitotoxic susceptibility in the various basal forebrain regions of mammals. # 2006 Elsevier Ltd. All rights reserved." @default.
• W2188765627 created "2016-06-24" @default.
• W2188765627 creator A5036913519 @default.
• W2188765627 creator A5067802852 @default.
• W2188765627 creator A5071250011 @default.
• W2188765627 creator A5089884032 @default.
• W2188765627 date "2006-01-01" @default.
• W2188765627 modified "2023-09-22" @default.
• W2188765627 title "Rapid communication Differential co-expression of AMPA receptor subunits in substance P receptor-containing neurons of basal forebrain regions of C57/BL mice" @default.
• W2188765627 cites W119932520 @default.
• W2188765627 cites W1522048223 @default.
• W2188765627 cites W1540911990 @default.
• W2188765627 cites W1551261730 @default.
• W2188765627 cites W1571037251 @default.
• W2188765627 cites W1860985526 @default.
• W2188765627 cites W1968549810 @default.
• W2188765627 cites W1969041354 @default.
• W2188765627 cites W1969906958 @default.
• W2188765627 cites W1972183007 @default.
• W2188765627 cites W1973013584 @default.
• W2188765627 cites W1975384649 @default.
• W2188765627 cites W1976546825 @default.
• W2188765627 cites W1976837940 @default.
• W2188765627 cites W1997862361 @default.
• W2188765627 cites W1999514420 @default.
• W2188765627 cites W2002125908 @default.
• W2188765627 cites W2021280501 @default.
• W2188765627 cites W2021540475 @default.
• W2188765627 cites W2023786646 @default.
• W2188765627 cites W2027830880 @default.
• W2188765627 cites W2036466038 @default.
• W2188765627 cites W2040954045 @default.
• W2188765627 cites W2048914428 @default.
• W2188765627 cites W2051208171 @default.
• W2188765627 cites W2051942658 @default.
• W2188765627 cites W2055232873 @default.
• W2188765627 cites W2058684269 @default.
• W2188765627 cites W2059214757 @default.
• W2188765627 cites W2060271345 @default.
• W2188765627 cites W2062501916 @default.
• W2188765627 cites W2064469548 @default.
• W2188765627 cites W2065709888 @default.
• W2188765627 cites W2073201555 @default.
• W2188765627 cites W2074949986 @default.
• W2188765627 cites W2080071110 @default.
• W2188765627 cites W2081319561 @default.
• W2188765627 cites W2081422759 @default.
• W2188765627 cites W2081991873 @default.
• W2188765627 cites W2083890595 @default.
• W2188765627 cites W2085570783 @default.
• W2188765627 cites W2087571754 @default.
• W2188765627 cites W2088015152 @default.
• W2188765627 cites W2092045031 @default.
• W2188765627 cites W2093225726 @default.
• W2188765627 cites W2095063454 @default.
• W2188765627 cites W2099597342 @default.
• W2188765627 cites W2104659088 @default.
• W2188765627 cites W2115359671 @default.
• W2188765627 cites W2118827322 @default.
• W2188765627 cites W2124192107 @default.
• W2188765627 cites W2129168701 @default.
• W2188765627 cites W2129766810 @default.
• W2188765627 cites W2159348568 @default.
• W2188765627 cites W2161708333 @default.
• W2188765627 cites W2172113265 @default.
• W2188765627 hasPublicationYear "2006" @default.
• W2188765627 type Work @default.
• W2188765627 sameAs 2188765627 @default.
• W2188765627 citedByCount "0" @default.
• W2188765627 crossrefType "journal-article" @default.
• W2188765627 hasAuthorship W2188765627A5036913519 @default.
• W2188765627 hasAuthorship W2188765627A5067802852 @default.
• W2188765627 hasAuthorship W2188765627A5071250011 @default.
• W2188765627 hasAuthorship W2188765627A5089884032 @default.
• W2188765627 hasConcept C104966671 @default.
• W2188765627 hasConcept C126322002 @default.
• W2188765627 hasConcept C160268369 @default.
• W2188765627 hasConcept C169760540 @default.
• W2188765627 hasConcept C170493617 @default.
• W2188765627 hasConcept C22885893 @default.
• W2188765627 hasConcept C2776287375 @default.
• W2188765627 hasConcept C2776818558 @default.
• W2188765627 hasConcept C2777705664 @default.
• W2188765627 hasConcept C2778187257 @default.
• W2188765627 hasConcept C2778205193 @default.
• W2188765627 hasConcept C2779305214 @default.
• W2188765627 hasConcept C2779715522 @default.
• W2188765627 hasConcept C2780278869 @default.
• W2188765627 hasConcept C529278444 @default.
• W2188765627 hasConcept C55493867 @default.
• W2188765627 hasConcept C61174792 @default.
• W2188765627 hasConcept C71924100 @default.
• W2188765627 hasConcept C86803240 @default.
• W2188765627 hasConcept C95444343 @default.
• W2188765627 hasConceptScore W2188765627C104966671 @default.
• W2188765627 hasConceptScore W2188765627C126322002 @default.
• W2188765627 hasConceptScore W2188765627C160268369 @default.
• W2188765627 hasConceptScore W2188765627C169760540 @default.
• W2188765627 hasConceptScore W2188765627C170493617 @default.
• W2188765627 hasConceptScore W2188765627C22885893 @default.

• next