Matches in SemOpenAlex for { <https://semopenalex.org/work/W2188774292> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2188774292 abstract "Many researchers assume that laboratory rats have poor vision, and accordingly, that they need not consider differences in the visual function of rats as a consequence of strain or experience. Currently, it is not specifically known whether rat domestication has negatively affected the visual function of laboratory rat strains, what the effects of strain albinism are on rat visual function, or whether there are strain differences in the visual function of laboratory rats that are independent of pigmentation. In order to address these questions, we measured psychophysically the vertical grating acuity of three pigmented (Dark Agouti, Fisher/ Norway, Long-Evans) and three albino (Fisher-344, Sprague/Dawley, Wistar) strains of laboratory rats, and compared their acuity with that of wild rats. The grating thresholds of Dark Agouti, Long-Evans and wild strains clustered around 1.0 cycle/degree (c/d) and did not significantly differ from one another. Fisher/Norway rats, however, had a significantly higher threshold of 1.5 c/d. The grating thresholds of Fisher-344, Sprague/Dawley, and Wistar strains, which were clustered around 0.5 c/d, were significantly lower than those of the pigmented strains. These data demonstrate that there is significant strain variability in the visual function of laboratory rats. Domestication of Long-Evans and Dark Agouti strains does not appear to have compromised visual acuity, but in the case of Fisher/Norway rats, selective breeding may have enhanced their acuity. Strain selection associated with albinism, however, appears to have consistently impaired visual acuity. Therefore, a consideration of strain differences in visual function should accompany the selection of a rat model for behavioral tasks that involve vision, or when comparing visuo-behavioral measurements across rat strains. # 2002 Elsevier Science B.V. All rights reserved." @default.
- W2188774292 created "2016-06-24" @default.
- W2188774292 creator A5008141205 @default.
- W2188774292 creator A5018359506 @default.
- W2188774292 creator A5022434691 @default.
- W2188774292 creator A5078207527 @default.
- W2188774292 date "2002-01-01" @default.
- W2188774292 modified "2023-09-27" @default.
- W2188774292 title "Research report Variation in visual acuity within pigmented, and between pigmented and albino rat strains" @default.
- W2188774292 cites W2050789136 @default.
- W2188774292 hasPublicationYear "2002" @default.
- W2188774292 type Work @default.
- W2188774292 sameAs 2188774292 @default.
- W2188774292 citedByCount "1" @default.
- W2188774292 crossrefType "journal-article" @default.
- W2188774292 hasAuthorship W2188774292A5008141205 @default.
- W2188774292 hasAuthorship W2188774292A5018359506 @default.
- W2188774292 hasAuthorship W2188774292A5022434691 @default.
- W2188774292 hasAuthorship W2188774292A5078207527 @default.
- W2188774292 hasConcept C105702510 @default.
- W2188774292 hasConcept C118487528 @default.
- W2188774292 hasConcept C134387633 @default.
- W2188774292 hasConcept C2775902910 @default.
- W2188774292 hasConcept C2776199212 @default.
- W2188774292 hasConcept C2778022156 @default.
- W2188774292 hasConcept C2778257484 @default.
- W2188774292 hasConcept C54355233 @default.
- W2188774292 hasConcept C71924100 @default.
- W2188774292 hasConcept C86803240 @default.
- W2188774292 hasConceptScore W2188774292C105702510 @default.
- W2188774292 hasConceptScore W2188774292C118487528 @default.
- W2188774292 hasConceptScore W2188774292C134387633 @default.
- W2188774292 hasConceptScore W2188774292C2775902910 @default.
- W2188774292 hasConceptScore W2188774292C2776199212 @default.
- W2188774292 hasConceptScore W2188774292C2778022156 @default.
- W2188774292 hasConceptScore W2188774292C2778257484 @default.
- W2188774292 hasConceptScore W2188774292C54355233 @default.
- W2188774292 hasConceptScore W2188774292C71924100 @default.
- W2188774292 hasConceptScore W2188774292C86803240 @default.
- W2188774292 hasLocation W21887742921 @default.
- W2188774292 hasOpenAccess W2188774292 @default.
- W2188774292 hasPrimaryLocation W21887742921 @default.
- W2188774292 hasRelatedWork W1491722899 @default.
- W2188774292 hasRelatedWork W188247612 @default.
- W2188774292 hasRelatedWork W191463960 @default.
- W2188774292 hasRelatedWork W1978868754 @default.
- W2188774292 hasRelatedWork W1986706346 @default.
- W2188774292 hasRelatedWork W1993930083 @default.
- W2188774292 hasRelatedWork W2016101013 @default.
- W2188774292 hasRelatedWork W2019468580 @default.
- W2188774292 hasRelatedWork W2022620879 @default.
- W2188774292 hasRelatedWork W2025969334 @default.
- W2188774292 hasRelatedWork W2057226184 @default.
- W2188774292 hasRelatedWork W2079643503 @default.
- W2188774292 hasRelatedWork W2081003129 @default.
- W2188774292 hasRelatedWork W2090121967 @default.
- W2188774292 hasRelatedWork W231438417 @default.
- W2188774292 hasRelatedWork W2317918119 @default.
- W2188774292 hasRelatedWork W3030268528 @default.
- W2188774292 hasRelatedWork W82769527 @default.
- W2188774292 hasRelatedWork W2603000990 @default.
- W2188774292 isParatext "false" @default.
- W2188774292 isRetracted "false" @default.
- W2188774292 magId "2188774292" @default.
- W2188774292 workType "article" @default.