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- W2188792204 abstract "The aim of the present study is to evaluate the anti-diarrhoeal activity of the petroleum ether extract of leaves of Quisqualis indica L. against experimentally induced diarrhoea. Petroleum ether extract of the drug were evaluated for antidiarrhoeal activity, using experimentally induced diarrhoea models: castor-oil induced diarrhoea, and charcoal induced gastrointestinal motility test in albino wistar rats of either sex. The earlier reported preliminary phytochemical screening of petroleum ether extracts revealed the presence of alkaloids, glycosides, flavonoids, tannins and phenolic compounds. petroleum ether extract of Quisqualis indica L. leaves at the doses (100, 200 mg/kg, p.o) were administered through the oral route. The plant extracts exhibited dose dependent anti-diarrhoeal effects in the all treated groups and the results were compared with that of standard drugs (Loperamide (3 mg/kg, p.o) and Atropine sulphate (0.1 mg/kg intraperitoneal), respectively as reference standard drugs. Statistically processed results support the conclusion, that the petroleum ether extracts of Quisqualis indica L. leaves (100 mg/kg and 200 mg/kg) possesses dose dependent, significant (P<0.05) antidiarrhoeal activity against experimentally induced diarrhoea." @default.
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- W2188792204 date "2013-06-01" @default.
- W2188792204 modified "2023-09-27" @default.
- W2188792204 title "Evaluation of anti-diarrhoeal activity of Quisqualis indica L. leaves" @default.
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