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- W2188966393 abstract "Dietary histidine has been shown to elevate circulating free histidine and plasma histamine concentration in murine models as much as 6- fold. Bladder mastocytosis is a hallmark of feline interstitial cystitis, and histidine is stored in mast cells and converted to histamine for signaling and inflamma tion by the enzyme histidine decarboxylase. Elevated dietary histidine may represent a risk factor for heightened mast cell responses. Nine healthy adult female shorthair cats were used in random crossover experiment with fixed treatment sequences to test the effects of dietary histidine (0.6, 1.0, and 1.4% DM) on histamine in blood and urine. The dry-extruded test foods were fed in sufficient amounts to maintain ideal body weight. Each experimental period was preceded by a 7-day wash out period, in which the 0.6% histidine diet was fed, followed by a 14-day feeding period of" @default.
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- W2188966393 date "2012-01-01" @default.
- W2188966393 modified "2023-09-29" @default.
- W2188966393 title "Influence of Dietary Histidine on Basophil Release, Circulating Concentration, and Urinary Excretion of Histamine in Domestic Felines" @default.
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