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- W2189051567 abstract "Faecal tumour M2-Pyruvate kinase levels were measured in a large, unselected, asymptomatic screening population to determine its specificity and to demonstrate the distribution in different age groups. Faecal tumour M2-Pyruvate kinase levels were measured with a sandwich ELISA in stool samples of 4854 screened volunteers. The levels were below the cutoff value of 4.0 kU/L in 4425 of the population. This means that 91.2% of all the people we screened had faecal tumour M2-Pruvate kinase levels within the normal, non-pathological range. The percentage of individuals with elevated tumour M2-Pruvate kinase concentrations increased from 6.9% in the age group of 30–39 years to 16.0% in the age group of 70–79 years. The estimated specificity range of the test, using prevalence data and our study results was 0.93-0.96. These results underline the usefulness of the tumour M2-Pruvate kinase stool test as a non-invasive, easy, fast, and economical method for colorectal cancer screening." @default.
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- W2189051567 date "2009-01-01" @default.
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- W2189051567 title "The faecal tumour M2-PK screening test for invasive & pre-invasive colorectal cancer: estimated specificity & results as a function of age for a study population of 4854 volunteers" @default.
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