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- W2189068271 abstract "Objective: To outline a series of cases demonstrating neurologic complications in children with Influenza infection. The ongoing 2009 influenza A pandemic (pH1N1) presents significant challenges to the field of pediatric critical care and requires increased awareness of new presentations and sequelae of infection. Since World Health Organization declared a pH1N1 pandemic, much attention has been focused on its respiratory manifestations of the illness, but limited information regarding neurologic complications has been reported. Design: Case series. Setting: Pediatric intensive care unit of a tertiary care medical facility. Patients: Four children admitted to the pediatric intensive care unit between March and November 2009 at the Children’s Hospital of Pittsburgh with altered mental status and influenza infection. Interventions: ———————-. Measurements and Main Results: The clinical course was extracted by chart review and is summarized. All children demonstrated a coryzal prodrome, fever, and altered level of consciousness at admission, and one child presented with clinical seizures. Diagnostic studies performed to establish a diagnosis are summarized. All children had abnormal electroencephalograms early in their intensive care unit course and 50% had abnormal imaging studies. All children survived but 50% had neurologic deficits at hospital discharge. Conclusion: We conclude that 2009 influenza A (pH1N1) can cause significant acute and residual neurologic sequelae. Clinicians should consider Influenza within a comprehensive differential diagnosis in children with unexplained mental status changes during periods of pandemic influenza. (Pediatr Crit Care Med 2010; 11:000‐000)" @default.
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- W2189068271 date "2010-01-01" @default.
- W2189068271 modified "2023-09-27" @default.
- W2189068271 title "Neurological sequelae of pH1N1 influenza in children: A case series observed during a pandemic*" @default.
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