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- W2189096324 abstract "Aim: Buchholzia coriacea had been claimed to have medicinal properties. It has been used by the locals, in Idemili area of Anambra State, Nigeria to manage frequent ‘stooling’. This study is therefore aimed at determining this claim which will also serve as a criteria to recommend the ethanopharmacological use of the plant. Methodology: The leaves of Buchholzia coriacea were dried, powdered and extracted by cold maceration with methanol for 48hrs, it was concentrated using rotary evaporator. The anti-diarrhoeal activity of the leaves extract was investigated using castor oil induced diarrhoea in rats. Whereas antispasmodic study was investigated using charcoal meal in tragacanth mucilage. Phytochemical evaluation revealed the presence of tannins, flavonoids, alkaloids, glycosides, and saponins . Result: Buchholzia coriacea leaves extract (100 -500 mg/kg) caused a significant and dose-related inhibition of the frequency of diarrhoeic drops in rats (p< 0.05) and prolonged the time for diarrhoea induction. It also exhibited antispasmodic effect. Conclusion: The claimed benefits of Buchholzia coriacea in traditional medical management of diarrhea as well as “stomach bite”, could be supported by the results of this investigation." @default.
- W2189096324 created "2016-06-24" @default.
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- W2189096324 date "2012-01-01" @default.
- W2189096324 modified "2023-09-27" @default.
- W2189096324 title "THE PHYTOCHEMICAL, ANTISPASMODIC AND ANTIDIARRHOEA PROPERTIES OF THE METHANOL EXTRACT OF THE LEAVES OF BUCHHOLZIA CORIACEA FAMILY CAPPARACEAE Research Article" @default.
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