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- W2189196834 abstract "Simple, sensitive, rapid, accurate and precise dual wavelength spectrophotometric method described for the simultaneous estimation of Esomeprazole (ESO) and Levosulpiride (LSP) in combined dosage form. The utility of dual wavelength data processing program is its ability to calculate unknown concentration of components of interest in a mixture containing an interfering component. The principle for dual wavelength method is “The absorbance difference between two points on the mixture spectr directly proportional to the concentration of the component of interest”. The method was based on determination of ESO at the absorbance difference between 289.20 nm and 257.60 nm and LSP at the absorbance difference between 302 nm and 226.40 nm. The the concentration range of 4-24 μg/ml and 5 respectively. The method was successfully applied to pharmaceutical dosage form because no interference from the excipients was found. The suitability of this me thod for the quantitative determination of ESO and LSP was proved by validation. The proposed method was found to be simple and sensitive for the routine quality control application of ESO and LSP in capsule dosage form. The results of analysis have been v statistically and by recovery studies." @default.
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- W2189196834 date "2013-01-01" @default.
- W2189196834 modified "2023-09-24" @default.
- W2189196834 title "DEVELOPMENT AND VALIDATION OF DUAL WAVELENGTH METHOD FOR SIMULTANEOUS ESTIMATION OF ESOMEPRAZOLE AND LEVOSULPIRIDE IN COMBINED CAPSULE DOSAGE FORM" @default.
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