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- W2189228210 abstract "Acute phase proteins (APPs) are serum proteins whose concentrations change after infectious and infl ammatory disease, and cancer. The aims of this study were to evaluate changes in APPs concentration and to correlate these fi ndings with histological classifi cation and WBC in female dogs with mammary tumors. APPs were studied in 45 female dogs with mammary tumor distributed in the following groups: benign (n=13), malignant without tumor ulceration (n=24), and malignant with tumor ulceration (n=8). SDS-polyacrylamide gel (SDS-PAGE) electrophoresis was used to measure APPs concentrations (albumin, ceruloplasmin, transferrin, haptoglobinHp, α-1-acid glycoprotein and α-1-antitrypsin) and ultrasensitive assay was used to evaluate serum C-reactive protein (CRP). Patients with malignant mammary neoplasia plus ulceration had signifi cant increase of CRP and Hp, and had decreased levels of albumin (P<0.05, one-Way ANOVA and Dunn Test). Positive correlation among APPs and infl ammatory leukocytosis were observed (P=0.002, Fisher test). No correlation was observed between APPs and histological subtype. In conclusion, combined changes of CRP, Hp and albumin may be used as a prediagnostic tool and prognosis in dogs with mammary tumors." @default.
- W2189228210 created "2016-06-24" @default.
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- W2189228210 date "2013-01-01" @default.
- W2189228210 modified "2023-09-27" @default.
- W2189228210 title "Michelly Kheidy Borges Battisti I Daniella Matos da Silva I Mhayara Samile de Oliveira Reusing I Olair Carlos Beltrame I Elizabeth Moreira dos Santos Schmidt II José Jurandir Fagliari III Rosângela Locatelli Dittrich I Simone Domit Guérios I" @default.
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- W2189228210 hasPublicationYear "2013" @default.
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