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• W2189244166 abstract "Heart disease and Diabetes possess the first and second leading cause of death in the world and people are suffering from chronic kidney disease are likely more tend to suffer from hypercholesterolemia. Alpha-lipoic acid is unsaturated fatty acids having strong anti-oxidative properties. The aim of this study was to characterize alpha-lipoic acid as a cholesterol reducer for acetaminophen induced uremic rats. The study was performed on thirty male albino rats. Plasma total cholesterol, triglyceride levels, liver enzymes assay and hematologic parameters were performed to investigate its cholesterol reducing properties. In this present study it was observed that receiving acetaminophen intraperitoneally for 10 days significantly decreased Hb level and RBC count compared with control. The present study demonstrated that cholesterol and triglycerides levels were significantly higher in acetaminophen treated group compare to control. Alpha-lipoic acid ameliorates cholesterol and triglyceride levels at high dose due to its anti-oxidative properties. The ALP and ALT were significantly higher in acetaminophen treated group compared with control group. It may be hypothesized that there was a cholesterol reducing properties of alpha-lipoic acid at higher dose." @default.
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• W2189244166 date "2014-01-01" @default.
• W2189244166 modified "2023-09-22" @default.
• W2189244166 title "Alpha-Lipoic Acid A Cholesterol Reducer for Targeting Acetaminophen Induced Uremic Male Albino Rat Models" @default.
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• W2189244166 hasPublicationYear "2014" @default.
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