Matches in SemOpenAlex for { <https://semopenalex.org/work/W2189285124> ?p ?o ?g. }
- W2189285124 abstract "CD4 + regulatory T cells (Treg cells) that produce interleukin 10 (IL-10) are important contributors to immune homeostasis. We generated mice with a ‘dual-reporter’ system of the genes encoding IL-10 and the transcription factor Foxp3 to track Treg subsets based on coordinate or differential expression of these genes. Secondary lymphoid tissues, lung and liver had enrichment of Foxp3 + IL-10 – Treg cells, whereas the large and small intestine had enrichment of Foxp3 + IL-10 + and Foxp3 – IL-10 + Treg cells, respectively. Although negative for Il10 expression, both Foxp3 + and Foxp3 – CD4 + thymic precursor cells gave rise to peripheral IL-10 + Treg cells, with only Foxp3 – precursor cells giving rise to all Treg subsets. Each Treg subset developed in IL-10-deficient mice, but this was blocked by treatment with antibody to transforming growth factor-b. Thus, Foxp3 + and Foxp3 – precursor cells give rise to peripheral IL-10-expressing Treg cells by a mechanism dependent on transforming growth factor-b and independent of IL-10." @default.
- W2189285124 created "2016-06-24" @default.
- W2189285124 creator A5023828240 @default.
- W2189285124 creator A5025364549 @default.
- W2189285124 creator A5028913632 @default.
- W2189285124 creator A5030125111 @default.
- W2189285124 creator A5039587112 @default.
- W2189285124 creator A5055018296 @default.
- W2189285124 creator A5059509899 @default.
- W2189285124 date "2007-01-01" @default.
- W2189285124 modified "2023-09-26" @default.
- W2189285124 title "Regulatory T cells expressing interleukin 10 develop from Foxp3 + and Foxp3 - precursor cells in the absence" @default.
- W2189285124 cites W1513672361 @default.
- W2189285124 cites W1515615230 @default.
- W2189285124 cites W1526621387 @default.
- W2189285124 cites W1530782041 @default.
- W2189285124 cites W1567420244 @default.
- W2189285124 cites W1752167169 @default.
- W2189285124 cites W1974781378 @default.
- W2189285124 cites W1976008320 @default.
- W2189285124 cites W1980069352 @default.
- W2189285124 cites W1980690619 @default.
- W2189285124 cites W1980780108 @default.
- W2189285124 cites W1982006380 @default.
- W2189285124 cites W1984146759 @default.
- W2189285124 cites W2002061924 @default.
- W2189285124 cites W2002726823 @default.
- W2189285124 cites W2003257616 @default.
- W2189285124 cites W2036500213 @default.
- W2189285124 cites W2041696905 @default.
- W2189285124 cites W2043796257 @default.
- W2189285124 cites W2055061339 @default.
- W2189285124 cites W2059283750 @default.
- W2189285124 cites W2065712492 @default.
- W2189285124 cites W2082992807 @default.
- W2189285124 cites W2084990572 @default.
- W2189285124 cites W2085918020 @default.
- W2189285124 cites W2095804489 @default.
- W2189285124 cites W2097811455 @default.
- W2189285124 cites W2100357356 @default.
- W2189285124 cites W2101700945 @default.
- W2189285124 cites W2103357560 @default.
- W2189285124 cites W2105204567 @default.
- W2189285124 cites W2111199584 @default.
- W2189285124 cites W2112866067 @default.
- W2189285124 cites W2116394003 @default.
- W2189285124 cites W2120010406 @default.
- W2189285124 cites W2124621398 @default.
- W2189285124 cites W2130486201 @default.
- W2189285124 cites W2131678280 @default.
- W2189285124 cites W2134560060 @default.
- W2189285124 cites W2134648443 @default.
- W2189285124 cites W2136097155 @default.
- W2189285124 cites W2138656295 @default.
- W2189285124 cites W2139021664 @default.
- W2189285124 cites W2139191751 @default.
- W2189285124 cites W2141783094 @default.
- W2189285124 cites W2151550531 @default.
- W2189285124 cites W2155779547 @default.
- W2189285124 cites W2161074777 @default.
- W2189285124 cites W2162493503 @default.
- W2189285124 cites W2163855374 @default.
- W2189285124 cites W2165528446 @default.
- W2189285124 cites W2171598462 @default.
- W2189285124 cites W2776663677 @default.
- W2189285124 hasPublicationYear "2007" @default.
- W2189285124 type Work @default.
- W2189285124 sameAs 2189285124 @default.
- W2189285124 citedByCount "1" @default.
- W2189285124 countsByYear W21892851242013 @default.
- W2189285124 crossrefType "journal-article" @default.
- W2189285124 hasAuthorship W2189285124A5023828240 @default.
- W2189285124 hasAuthorship W2189285124A5025364549 @default.
- W2189285124 hasAuthorship W2189285124A5028913632 @default.
- W2189285124 hasAuthorship W2189285124A5030125111 @default.
- W2189285124 hasAuthorship W2189285124A5039587112 @default.
- W2189285124 hasAuthorship W2189285124A5055018296 @default.
- W2189285124 hasAuthorship W2189285124A5059509899 @default.
- W2189285124 hasConcept C131665280 @default.
- W2189285124 hasConcept C153911025 @default.
- W2189285124 hasConcept C159654299 @default.
- W2189285124 hasConcept C185592680 @default.
- W2189285124 hasConcept C187316574 @default.
- W2189285124 hasConcept C203014093 @default.
- W2189285124 hasConcept C2776090121 @default.
- W2189285124 hasConcept C2778296632 @default.
- W2189285124 hasConcept C2779727006 @default.
- W2189285124 hasConcept C79484868 @default.
- W2189285124 hasConcept C86803240 @default.
- W2189285124 hasConcept C8891405 @default.
- W2189285124 hasConcept C95444343 @default.
- W2189285124 hasConceptScore W2189285124C131665280 @default.
- W2189285124 hasConceptScore W2189285124C153911025 @default.
- W2189285124 hasConceptScore W2189285124C159654299 @default.
- W2189285124 hasConceptScore W2189285124C185592680 @default.
- W2189285124 hasConceptScore W2189285124C187316574 @default.
- W2189285124 hasConceptScore W2189285124C203014093 @default.
- W2189285124 hasConceptScore W2189285124C2776090121 @default.
- W2189285124 hasConceptScore W2189285124C2778296632 @default.
- W2189285124 hasConceptScore W2189285124C2779727006 @default.