Matches in SemOpenAlex for { <https://semopenalex.org/work/W2189342401> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2189342401 endingPage "693" @default.
- W2189342401 startingPage "679" @default.
- W2189342401 abstract "ABSTRACT From 1981 to 1983, 15,097 X-chromosomes were genetically extracted from a number of North American populations of D. melanogaster and were electrophoretically screened for rare mobility and activity variants of glucose-6-phosphate dehydrogenase (G6PD). Overall, 13 rare variants were recovered for a frequency of about 10-3. Eleven variants affect electrophoretic mobility and are apparently structural, and two variants exhibit low G6PD activity. One low activity variant is closely associated with a P-element insertion at 18D12-13—all of the variants were subjected to the previously described genetic scheme used to identify relative in vivo activity differences between the two common electrophoretic variants associated with the global polymorphism. Most of the rare variants exhibit apparent in vivo activities that are similar to one or the other of the common variants, and these specific rare variants appear to be geographically widespread. Several variants have significantly reduced function. All of the variants were measured for larval specific activity for G6PD as a first measure of in vitro activity. It appears that specific activity alone is not a sufficient predictor for G6PD in vivo function." @default.
- W2189342401 created "2016-06-24" @default.
- W2189342401 creator A5001914862 @default.
- W2189342401 creator A5060495478 @default.
- W2189342401 date "1986-07-01" @default.
- W2189342401 modified "2023-10-12" @default.
- W2189342401 title "<i>IN VIVO</i> FUNCTION OF RARE <i>G6pd</i> VARIANTS FROM NATURAL POPULATIONS OF <i>DROSOPHILA MELANOGASTER</i>" @default.
- W2189342401 cites W1820644981 @default.
- W2189342401 cites W1825306762 @default.
- W2189342401 cites W1866648957 @default.
- W2189342401 cites W1889077695 @default.
- W2189342401 cites W1912109328 @default.
- W2189342401 cites W2023346689 @default.
- W2189342401 cites W2053090649 @default.
- W2189342401 cites W2061999006 @default.
- W2189342401 cites W2065871570 @default.
- W2189342401 cites W2068252909 @default.
- W2189342401 cites W2086102180 @default.
- W2189342401 cites W2088889483 @default.
- W2189342401 cites W2106962907 @default.
- W2189342401 cites W2133917963 @default.
- W2189342401 cites W2150052811 @default.
- W2189342401 cites W2182655219 @default.
- W2189342401 doi "https://doi.org/10.1093/genetics/113.3.679" @default.
- W2189342401 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1202862" @default.
- W2189342401 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17246336" @default.
- W2189342401 hasPublicationYear "1986" @default.
- W2189342401 type Work @default.
- W2189342401 sameAs 2189342401 @default.
- W2189342401 citedByCount "19" @default.
- W2189342401 crossrefType "journal-article" @default.
- W2189342401 hasAuthorship W2189342401A5001914862 @default.
- W2189342401 hasAuthorship W2189342401A5060495478 @default.
- W2189342401 hasBestOaLocation W21893424011 @default.
- W2189342401 hasConcept C104317684 @default.
- W2189342401 hasConcept C127716648 @default.
- W2189342401 hasConcept C14036430 @default.
- W2189342401 hasConcept C207001950 @default.
- W2189342401 hasConcept C2776041557 @default.
- W2189342401 hasConcept C2776998849 @default.
- W2189342401 hasConcept C2780104201 @default.
- W2189342401 hasConcept C54355233 @default.
- W2189342401 hasConcept C86803240 @default.
- W2189342401 hasConceptScore W2189342401C104317684 @default.
- W2189342401 hasConceptScore W2189342401C127716648 @default.
- W2189342401 hasConceptScore W2189342401C14036430 @default.
- W2189342401 hasConceptScore W2189342401C207001950 @default.
- W2189342401 hasConceptScore W2189342401C2776041557 @default.
- W2189342401 hasConceptScore W2189342401C2776998849 @default.
- W2189342401 hasConceptScore W2189342401C2780104201 @default.
- W2189342401 hasConceptScore W2189342401C54355233 @default.
- W2189342401 hasConceptScore W2189342401C86803240 @default.
- W2189342401 hasIssue "3" @default.
- W2189342401 hasLocation W21893424011 @default.
- W2189342401 hasLocation W21893424012 @default.
- W2189342401 hasOpenAccess W2189342401 @default.
- W2189342401 hasPrimaryLocation W21893424011 @default.
- W2189342401 hasRelatedWork W1799375311 @default.
- W2189342401 hasRelatedWork W2018569889 @default.
- W2189342401 hasRelatedWork W2019606006 @default.
- W2189342401 hasRelatedWork W2060450464 @default.
- W2189342401 hasRelatedWork W2078833601 @default.
- W2189342401 hasRelatedWork W2105969549 @default.
- W2189342401 hasRelatedWork W2134964329 @default.
- W2189342401 hasRelatedWork W2408945988 @default.
- W2189342401 hasRelatedWork W4283035092 @default.
- W2189342401 hasRelatedWork W4287832753 @default.
- W2189342401 hasVolume "113" @default.
- W2189342401 isParatext "false" @default.
- W2189342401 isRetracted "false" @default.
- W2189342401 magId "2189342401" @default.
- W2189342401 workType "article" @default.