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• W2189352963 endingPage "247" @default.
• W2189352963 startingPage "227" @default.
• W2189352963 abstract "Endometriosis is an estrogen-dependent chronic disease of women of fertile age requiring chronic therapy. Although available drugs have good efficacy and safety profiles, some patients experience partial or no improvement of pain with conventional treatment and recurrence of symptoms after discontinuation of the therapies. For these reasons, many new compounds are currently under investigation for the treatment of endometriosis.This review offers the reader a complete and updated overview on emerging therapies for the treatment of endometriosis. The authors describe, in detail, the laboratory and clinical studies on these therapies and highlight the potential advantages and limitations associated with the administration of these new agents.Gonadotropin-releasing hormone antagonists are the most intriguing emerging agents for the treatment of patients with endometriosis. It should be noted that while there are a number of drugs under investigation, a large majority of these new compounds have only been investigated in laboratory studies with more extensive research required to better elucidate their efficacy and safety profiles." @default.
• W2189352963 created "2016-06-24" @default.
• W2189352963 creator A5033337879 @default.
• W2189352963 creator A5075844307 @default.
• W2189352963 date "2015-12-19" @default.
• W2189352963 modified "2023-09-26" @default.
• W2189352963 title "An overview of early drug development for endometriosis" @default.
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