Matches in SemOpenAlex for { <https://semopenalex.org/work/W2189398126> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2189398126 abstract "The purpose of this report is to describe the occurrence and pathology of a spontaneous and rare brain tumor in a strain of rat commonly employed for drug and chemical safety testing. Glioblastoma multiforme is another term for “malignant astrocytoma” (Grade 3 or 4) and is characterized by cellular and nuclear hyperchromasia and pleomorphism, multinucleated giant cells and pallisading necrosis. The tumor exhibits highly aggressive invasive behavior. In contrast, “anaplastic glioma” is a term applied to any malignant tumor of glial cells including those containing astrocytes. Often, there are variable mixtures of cell types within a given tumor. None of these anaplastic gliomas exhibit the degree of anaplasia or invasive behavior seen in the tumor of this report. Primary brain tumors in rats are infrequent compared to tumors found in other organ systems. In a recent report, astrocytoma was the most frequent glial cell tumor in Sprague-Dawley rats with an incidence of 28/2,630 in males and 18/2,765 in females (3). This literature report included a total of 88 brain tumors from 5,395 untreated controls and 297 brain tumors from a total of 19,251 rats examined in the combined control and treated groups. None of the astrocytomas reported satisfied the criteria needed for designation as glioblastoma multiforme. A 1974 report of 38 naturally occurring brain tumors found in 4 1,000 Sprague-Dawley rats over a 5-year period included 10 astrocytomas or" @default.
- W2189398126 created "2016-06-24" @default.
- W2189398126 creator A5008935277 @default.
- W2189398126 creator A5029271605 @default.
- W2189398126 creator A5051170730 @default.
- W2189398126 date "1987-01-01" @default.
- W2189398126 modified "2023-09-26" @default.
- W2189398126 title "BRIEF COMMUNICATION Spontaneous Glioblastoma Multiforme in a Charles River CD Rat" @default.
- W2189398126 cites W1480878209 @default.
- W2189398126 cites W1503743426 @default.
- W2189398126 cites W1987277133 @default.
- W2189398126 cites W2031318281 @default.
- W2189398126 cites W2045002880 @default.
- W2189398126 cites W2410025711 @default.
- W2189398126 cites W2467141180 @default.
- W2189398126 cites W343231867 @default.
- W2189398126 hasPublicationYear "1987" @default.
- W2189398126 type Work @default.
- W2189398126 sameAs 2189398126 @default.
- W2189398126 citedByCount "0" @default.
- W2189398126 crossrefType "journal-article" @default.
- W2189398126 hasAuthorship W2189398126A5008935277 @default.
- W2189398126 hasAuthorship W2189398126A5029271605 @default.
- W2189398126 hasAuthorship W2189398126A5051170730 @default.
- W2189398126 hasConcept C142160229 @default.
- W2189398126 hasConcept C142724271 @default.
- W2189398126 hasConcept C204232928 @default.
- W2189398126 hasConcept C2778227246 @default.
- W2189398126 hasConcept C2778880634 @default.
- W2189398126 hasConcept C2779083369 @default.
- W2189398126 hasConcept C2779130545 @default.
- W2189398126 hasConcept C2780263296 @default.
- W2189398126 hasConcept C502942594 @default.
- W2189398126 hasConcept C71924100 @default.
- W2189398126 hasConcept C86803240 @default.
- W2189398126 hasConceptScore W2189398126C142160229 @default.
- W2189398126 hasConceptScore W2189398126C142724271 @default.
- W2189398126 hasConceptScore W2189398126C204232928 @default.
- W2189398126 hasConceptScore W2189398126C2778227246 @default.
- W2189398126 hasConceptScore W2189398126C2778880634 @default.
- W2189398126 hasConceptScore W2189398126C2779083369 @default.
- W2189398126 hasConceptScore W2189398126C2779130545 @default.
- W2189398126 hasConceptScore W2189398126C2780263296 @default.
- W2189398126 hasConceptScore W2189398126C502942594 @default.
- W2189398126 hasConceptScore W2189398126C71924100 @default.
- W2189398126 hasConceptScore W2189398126C86803240 @default.
- W2189398126 hasLocation W21893981261 @default.
- W2189398126 hasOpenAccess W2189398126 @default.
- W2189398126 hasPrimaryLocation W21893981261 @default.
- W2189398126 hasRelatedWork W1502708042 @default.
- W2189398126 hasRelatedWork W188132093 @default.
- W2189398126 hasRelatedWork W1997541085 @default.
- W2189398126 hasRelatedWork W2014510598 @default.
- W2189398126 hasRelatedWork W2052361488 @default.
- W2189398126 hasRelatedWork W2060771417 @default.
- W2189398126 hasRelatedWork W2090026039 @default.
- W2189398126 hasRelatedWork W2093925042 @default.
- W2189398126 hasRelatedWork W2224163413 @default.
- W2189398126 hasRelatedWork W2253258434 @default.
- W2189398126 hasRelatedWork W2287326647 @default.
- W2189398126 hasRelatedWork W2415353881 @default.
- W2189398126 hasRelatedWork W2497657610 @default.
- W2189398126 hasRelatedWork W2803460161 @default.
- W2189398126 hasRelatedWork W3114959750 @default.
- W2189398126 hasRelatedWork W3185383134 @default.
- W2189398126 hasRelatedWork W57293657 @default.
- W2189398126 hasRelatedWork W72435381 @default.
- W2189398126 hasRelatedWork W75914309 @default.
- W2189398126 hasRelatedWork W2140794932 @default.
- W2189398126 isParatext "false" @default.
- W2189398126 isRetracted "false" @default.
- W2189398126 magId "2189398126" @default.
- W2189398126 workType "article" @default.