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• W2189404920 abstract "Abstract A murine Interleukin-2 (IL-2)-dependent T-cell line, CTLL-2, was infected with a retrovirus carrying the mouse c-myc cDNA and the Tn-5 neogene. Transduced cells were selected in the presence of Geneticin sulfate (G418); these cells were shown to express both the endogenous and the transduced c-myc genes. The IL-2 requirement of these cells was then found to be significantly reduced. The cells did not express IL-2 mRNA nor did they produce an activity myogenic for CTLL-2 cells. This suggests that the reduction of IL-2 dependence observed following retroviral transduction of c-myc is caused by a nonautocrine mechanism." @default.
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• W2189404920 date "1988-12-01" @default.
• W2189404920 modified "2023-10-09" @default.
• W2189404920 title "Infection of a Murine T-Cell Line With a Retrovirus Carrying c-<i>myc</i> Decreases the Interleukin-2 Cell Dependence by a Nonautocrine Mechanism" @default.
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• W2189404920 doi "https://doi.org/10.1002/jlb.44.6.559" @default.
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