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- W2189413086 abstract "SUMMARY. A drug release system of a tetracycline loaded chitosan film with sustained antibiotic effect is described. Chitosan films (CF) containing tetracycline were prepared by casting method using acetic acid. The films were exposed to heat treatment at 90 oC, 120 oC or 150 oC (HCF). The effect of heat treatment on the water resistance to the chitosan films and tetracycline release was investigated. Heat treatment increase to a greater extent the water resistance of chitosan films. Heat treatment decreases the releases of tetracycline of the HCF when compared with CF. The antibiotic activity of tetracycline in chitosan film and heat-treated chitosan film at 150 oC was prolonged for 23 days approximately. The results indicated that the chitosan film was useful in tetracycline release such as for site-specific tetracycline controlled release in treatment of periodontal disease. RESUMEN. “Liberacion deTetraciclina de Peliculas de Quitosano”. El trabajo describe un sistema de dispositivo de liberacion lenta de droga de una pelicula de quitosano cargada de tetraciclina con efecto antibiotico sostenido." @default.
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- W2189413086 date "2008-01-01" @default.
- W2189413086 modified "2023-10-17" @default.
- W2189413086 title "Tetracycline Release from Chitosan Films" @default.
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