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- W2189440951 abstract "SUMMARY The present study was conducted to investigate the effects of epidural lidocaine and morphine on cardiovascular and respiratory systems in dogs anesthetized with halothane. A mixture of 0.26 ml/kg 2 % lidocaine and 2 mg morphine was introduced epidurally in 6 clinically healthy dogs anesthetized with halothane. The epidural administration of the mixture resulted in significant reduction in heart rate (HR; from 30 to 90 min intervals; P < 0.05), systolic arterial blood pressure (SAP), mean arterial blood pressure (MAP) (from 5 to 90 min intervals) and diastolic arterial blood pressure (DAP, from 30 to 120 min intervals) (P < 0.05). The cardiac output (CO) and the cardiac index (CI) decreased significantly between minutes 75 and 105 and minutes 75-90 respectively (P < 0.05). The changes in respiratory parameters were insignificant. In conclusion, the epidural application of a mixture of lidocaine and morphine was found to be a safe and effective method for achieving reliable anesthesia with minimal respiratory and moderate cardiovascular side effects." @default.
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- W2189440951 date "2001-01-01" @default.
- W2189440951 modified "2023-09-24" @default.
- W2189440951 title "Cardiovascular and respiratory effects of epidural lidocaine and morphine administered in dogs anaesthetized with halothane" @default.
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