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• W2189563414 abstract "Skin acts as a major target as well as a principal barrier for topical/transdermal drug delivery. Desp ite the many advantages of this system, the major obstacle is the low diffusion rate of drugs across the strat um corneum. One simple and convenient approach is application of drugs in formulation with elastic vesicl es or skin enhancers. Ethosomes are as novel vesicles in transdermal drug delivery show significant effects of drug penetration through the biological membrane with slight modification of well established drug car rier liposomes. Ethosomes are soft, malleable vesicles c omposed mainly of phospholipids, ethanol and water. The size of ethosome vesicles can be modulated from tens of nanometer to microns. The ethosomes can be prepared by Hot method, Cold method and optimized method. The evaluation parameters of ethosomes include visualization, vesicle size and zeta potent ial, entrapment efficiency. Ethosomes have been fou nd to be much more efficient at delivering drug to the sk in than either liposomes or hydroalcoholic solution . Hence it can be a effective dermal/transdermal de livery of bioactive agents." @default.
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• W2189563414 date "2014-01-01" @default.
• W2189563414 modified "2023-09-27" @default.
• W2189563414 title "ETHOSOMES- A NEW TRENDS IN VESICULAR APPROACHES FOR TOPICAL DRUG DELIVERY" @default.
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