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- W2189586009 abstract "The latex of Jatropha curcas is herbal medicine that is traditionally used as d ental pain relief. To abolish the pain, the latex was dri pped to the dental cavity, which may be exposed and may cause toxic effect to oral mucos a to happen. The aim of this study is to detect cytotoxicity of extracted latex of J. curcas to epithelial and fibroblast cells. The cells (1x10 5 ) were cultured in 96 well plates and allowed to attach for 5 days before treatment with serial conc entration of J. curcas for 24 h period. The cytotoxicity assay of epithelial and fi broblast cells was performed using MTT assay to determine inhibition concentration 50 (IC 50 ). In both of cells toxicity were detected dose-dependent, and IC 50 value for epithelial and fibroblast cells were 4339 μg/ml and 3876 μg/ml respectively. Morphologically both of treatmen t cells were smaller than control cells. Thus J. curcas was toxic to ephithelial and fibroblast cells" @default.
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- W2189586009 date "2012-01-01" @default.
- W2189586009 modified "2023-09-27" @default.
- W2189586009 title "In vitro cytotoxicity of Jatropha curcas in epithelial and fibroblast cells" @default.
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