FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2189610494> ?p ?o ?g. }

• W2189610494 endingPage "1164" @default.
• W2189610494 startingPage "1154" @default.
• W2189610494 abstract "In the light of multidrug resistance (MDR) among pathogenic microbes and cancer cells, membrane transporters have gained profound clinical significance. Chemotherapeutic failure, by far, has been attributed mainly to the robust and diverse array of these proteins, which are omnipresent in every stratum of the living world. Candida albicans, one of the major fungal pathogens affecting immunocompromised patients, also develops MDR during the course of chemotherapy. The pivotal membrane transporters that C. albicans has exploited as one of the strategies to develop MDR belongs to either the ATP binding cassette (ABC) or the major facilitator superfamily (MFS) class of proteins. The ABC transporter Candida drug resistance 1 protein (Cdr1p) is a major player among these transporters that enables the pathogen to outplay the battery of antifungals encountered by it. The promiscuous Cdr1 protein fulfills the quintessential need of a model to study molecular mechanisms of multidrug transporter regulation and structure-function analyses of asymmetric ABC transporters. In this review, we cover the highlights of two decades of research on Cdr1p that has provided a platform to study its structure-function relationships and regulatory circuitry for a better understanding of MDR not only in yeast but also in other organisms." @default.
• W2189610494 created "2016-06-24" @default.
• W2189610494 creator A5012939975 @default.
• W2189610494 creator A5052718025 @default.
• W2189610494 creator A5053366287 @default.
• W2189610494 creator A5066482635 @default.
• W2189610494 date "2015-12-01" @default.
• W2189610494 modified "2023-10-12" @default.
• W2189610494 title "The ABCs of Candida albicans Multidrug Transporter Cdr1" @default.
• W2189610494 cites W1486911736 @default.
• W2189610494 cites W1506832642 @default.
• W2189610494 cites W1544836540 @default.
• W2189610494 cites W1556261571 @default.
• W2189610494 cites W1608204567 @default.
• W2189610494 cites W1894827346 @default.
• W2189610494 cites W1964828092 @default.
• W2189610494 cites W1968624259 @default.
• W2189610494 cites W1970888920 @default.
• W2189610494 cites W1976277865 @default.
• W2189610494 cites W1991538652 @default.
• W2189610494 cites W1991863685 @default.
• W2189610494 cites W2001848963 @default.
• W2189610494 cites W2004248403 @default.
• W2189610494 cites W2011401590 @default.
• W2189610494 cites W2014642431 @default.
• W2189610494 cites W2018215572 @default.
• W2189610494 cites W2019342861 @default.
• W2189610494 cites W2022690723 @default.
• W2189610494 cites W2024173494 @default.
• W2189610494 cites W2027953675 @default.
• W2189610494 cites W2031072830 @default.
• W2189610494 cites W2035354696 @default.
• W2189610494 cites W2046157585 @default.
• W2189610494 cites W2050767064 @default.
• W2189610494 cites W2053731121 @default.
• W2189610494 cites W2066593428 @default.
• W2189610494 cites W2076308802 @default.
• W2189610494 cites W2080125656 @default.
• W2189610494 cites W2082968673 @default.
• W2189610494 cites W2083149296 @default.
• W2189610494 cites W2087555143 @default.
• W2189610494 cites W2094138644 @default.
• W2189610494 cites W2094285560 @default.
• W2189610494 cites W2098169836 @default.
• W2189610494 cites W2098563304 @default.
• W2189610494 cites W2101112015 @default.
• W2189610494 cites W2101319894 @default.
• W2189610494 cites W2101491044 @default.
• W2189610494 cites W2102500167 @default.
• W2189610494 cites W2107013040 @default.
• W2189610494 cites W2108097124 @default.
• W2189610494 cites W2115130703 @default.
• W2189610494 cites W2115265761 @default.
• W2189610494 cites W2117250841 @default.
• W2189610494 cites W2117511641 @default.
• W2189610494 cites W2118937378 @default.
• W2189610494 cites W2120323726 @default.
• W2189610494 cites W2120849142 @default.
• W2189610494 cites W2125270417 @default.
• W2189610494 cites W2126875126 @default.
• W2189610494 cites W2128528171 @default.
• W2189610494 cites W2132882111 @default.
• W2189610494 cites W2132937492 @default.
• W2189610494 cites W2136847126 @default.
• W2189610494 cites W2140917183 @default.
• W2189610494 cites W2140963713 @default.
• W2189610494 cites W2141752092 @default.
• W2189610494 cites W2144726832 @default.
• W2189610494 cites W2147757952 @default.
• W2189610494 cites W2153057813 @default.
• W2189610494 cites W2155134693 @default.
• W2189610494 cites W2156106543 @default.
• W2189610494 cites W2157149808 @default.
• W2189610494 cites W2158859009 @default.
• W2189610494 cites W2160155890 @default.
• W2189610494 cites W2162696679 @default.
• W2189610494 cites W2163483849 @default.
• W2189610494 cites W2164315014 @default.
• W2189610494 cites W2165333109 @default.
• W2189610494 cites W2167460646 @default.
• W2189610494 cites W2397257906 @default.
• W2189610494 cites W4235607015 @default.
• W2189610494 cites W615984982 @default.
• W2189610494 cites W2152128067 @default.
• W2189610494 doi "https://doi.org/10.1128/ec.00137-15" @default.
• W2189610494 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4664872" @default.
• W2189610494 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26407965" @default.
• W2189610494 hasPublicationYear "2015" @default.
• W2189610494 type Work @default.
• W2189610494 sameAs 2189610494 @default.
• W2189610494 citedByCount "84" @default.
• W2189610494 countsByYear W21896104942016 @default.
• W2189610494 countsByYear W21896104942017 @default.
• W2189610494 countsByYear W21896104942018 @default.
• W2189610494 countsByYear W21896104942019 @default.
• W2189610494 countsByYear W21896104942020 @default.
• W2189610494 countsByYear W21896104942021 @default.
• W2189610494 countsByYear W21896104942022 @default.

• next