FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2189948118> ?p ?o ?g. }

• W2189948118 endingPage "129" @default.
• W2189948118 startingPage "123" @default.
• W2189948118 abstract "Lipopolysaccharide derived from gastrointestinal microbiota contributes to systemic inflammation and obesity. Huang and Kraus propose that lipopolysaccharide is a major risk factor for osteoarthritis (OA), and suggest that therapeutic strategies for the reduction of systemic levels of lipopolysaccharide should be considered for prevention and treatment of OA. The nature of the gastrointestinal microbiome determines the reservoir of lipopolysaccharide, which can migrate from the gut into the circulation, where it contributes to low-grade inflammation. Osteoarthritis (OA) is a low-grade inflammatory condition, and the elevation of levels of lipopolysaccharide in association with obesity and metabolic syndrome could contribute to OA. A 'two- hit' model of OA susceptibility and potentiation suggests that lipopolysaccharide primes the proinflammatory innate immune response via Toll-like receptor 4 and that progression to a full-blown inflammatory response and structural damage of the joint results from coexisting complementary mechanisms, such as inflammasome activation or assembly by damage-associated molecular patterns in the form of fragmented cartilage-matrix molecules. Lipopolysaccharide could be considered a major hidden risk factor that provides a unifying mechanism to explain the association between obesity, metabolic syndrome and OA." @default.
• W2189948118 created "2016-06-24" @default.
• W2189948118 creator A5006916283 @default.
• W2189948118 creator A5071631262 @default.
• W2189948118 date "2015-12-10" @default.
• W2189948118 modified "2023-10-16" @default.
• W2189948118 title "Does lipopolysaccharide-mediated inflammation have a role in OA?" @default.
• W2189948118 cites W1541952406 @default.
• W2189948118 cites W1688319875 @default.
• W2189948118 cites W1802748781 @default.
• W2189948118 cites W1899371747 @default.
• W2189948118 cites W1965665343 @default.
• W2189948118 cites W1966994536 @default.
• W2189948118 cites W1969307566 @default.
• W2189948118 cites W1970166738 @default.
• W2189948118 cites W1977105811 @default.
• W2189948118 cites W1988760595 @default.
• W2189948118 cites W1991731944 @default.
• W2189948118 cites W1992113107 @default.
• W2189948118 cites W1999158053 @default.
• W2189948118 cites W1999500451 @default.
• W2189948118 cites W2004861927 @default.
• W2189948118 cites W2004864469 @default.
• W2189948118 cites W2007001334 @default.
• W2189948118 cites W2011509273 @default.
• W2189948118 cites W2013287212 @default.
• W2189948118 cites W2016390966 @default.
• W2189948118 cites W2017859009 @default.
• W2189948118 cites W2018172685 @default.
• W2189948118 cites W2018247592 @default.
• W2189948118 cites W2018285082 @default.
• W2189948118 cites W2019234798 @default.
• W2189948118 cites W2020913417 @default.
• W2189948118 cites W2028491403 @default.
• W2189948118 cites W2033649854 @default.
• W2189948118 cites W2034201007 @default.
• W2189948118 cites W2035242925 @default.
• W2189948118 cites W2035754392 @default.
• W2189948118 cites W2038773696 @default.
• W2189948118 cites W2044953211 @default.
• W2189948118 cites W2046712927 @default.
• W2189948118 cites W2047877478 @default.
• W2189948118 cites W2050228742 @default.
• W2189948118 cites W2050529805 @default.
• W2189948118 cites W2052179757 @default.
• W2189948118 cites W2063391683 @default.
• W2189948118 cites W2064062984 @default.
• W2189948118 cites W2064355487 @default.
• W2189948118 cites W2066901261 @default.
• W2189948118 cites W2067756762 @default.
• W2189948118 cites W2067773009 @default.
• W2189948118 cites W2071563106 @default.
• W2189948118 cites W2074128028 @default.
• W2189948118 cites W2079179318 @default.
• W2189948118 cites W2080242509 @default.
• W2189948118 cites W2080755877 @default.
• W2189948118 cites W2082566286 @default.
• W2189948118 cites W2086276639 @default.
• W2189948118 cites W2088336516 @default.
• W2189948118 cites W2088697466 @default.
• W2189948118 cites W2095833996 @default.
• W2189948118 cites W2097511131 @default.
• W2189948118 cites W2097885651 @default.
• W2189948118 cites W2105729460 @default.
• W2189948118 cites W2107489987 @default.
• W2189948118 cites W2110569929 @default.
• W2189948118 cites W2113691474 @default.
• W2189948118 cites W2114055603 @default.
• W2189948118 cites W2115850341 @default.
• W2189948118 cites W2116655288 @default.
• W2189948118 cites W2116688715 @default.
• W2189948118 cites W2124187551 @default.
• W2189948118 cites W2128493685 @default.
• W2189948118 cites W2129917444 @default.
• W2189948118 cites W2131536322 @default.
• W2189948118 cites W2134945818 @default.
• W2189948118 cites W2137068383 @default.
• W2189948118 cites W2138411980 @default.
• W2189948118 cites W2140598936 @default.
• W2189948118 cites W2141281036 @default.
• W2189948118 cites W2142251176 @default.
• W2189948118 cites W2144032514 @default.
• W2189948118 cites W2144275312 @default.
• W2189948118 cites W2146204370 @default.
• W2189948118 cites W2147866514 @default.
• W2189948118 cites W2150679087 @default.
• W2189948118 cites W2153157173 @default.
• W2189948118 cites W2153406190 @default.
• W2189948118 cites W2155190739 @default.
• W2189948118 cites W2156280702 @default.
• W2189948118 cites W2156769836 @default.
• W2189948118 cites W2159001939 @default.
• W2189948118 cites W2167062509 @default.
• W2189948118 cites W2168244623 @default.
• W2189948118 cites W2169364567 @default.
• W2189948118 cites W2170095557 @default.
• W2189948118 cites W2435896402 @default.
• W2189948118 cites W4234637910 @default.

• next