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• W2190160250 endingPage "341" @default.
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• W2190160250 abstract "A key aim in evolutionary biology is to deduce ancestral states to better understand the evolutionary origins of clades of interest and the diversification process(es) that has/have elaborated them. These ancestral deductions can hit difficulties when undetected loss events are misinterpreted as ancestral absences. With the ever-increasing amounts of animal genomic sequence data, we are gaining a much clearer view of the preponderance of differential gene losses across animal lineages. This has become particularly clear with recent progress in our understanding of the origins of the Hox/ParaHox developmental control genes relative to the earliest branching lineages of the animal kingdom: the sponges (Porifera), comb jellies (Ctenophora) and placozoans (Placozoa). These reassessments of the diversity and complexity of developmental control genes in the earliest animal ancestors need to go hand-in-hand with complementary advances in comparative morphology, phylogenetics and palaeontology to clarify our understanding of the complexity of the last common ancestor of all animals. The field is currently undergoing a shift from the traditional consensus of a sponge-like animal ancestor from which morphological and molecular elaboration subsequently evolved, to a scenario of a more complex animal ancestor, with subsequent losses and simplifications in various lineages." @default.
• W2190160250 created "2016-06-24" @default.
• W2190160250 creator A5086873853 @default.
• W2190160250 date "2015-12-04" @default.
• W2190160250 modified "2023-10-09" @default.
• W2190160250 title "The origin of the Hox/ParaHox genes, the Ghost Locus hypothesis and the complexity of the first animal" @default.
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• W2190160250 doi "https://doi.org/10.1093/bfgp/elv056" @default.
• W2190160250 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26637506" @default.
• W2190160250 hasPublicationYear "2015" @default.
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