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- W2190349574 abstract "Department of Gastroenterology, Sestre milosrdnice University Hospital, Zagreb, CroatiaSUMMARY Œ Hemangiopericytoma is a rare malignant vascular tumor deriving from pericytes. It usuallyoccurs in the extremities and retroperitoneum, and extremely rarely in the gastrointestinal tract. A case ofhemangiopericytoma in the gastroesophageal region is reported. A 56-year-old man was treated with H2-receptor antagonist for dyspeptic symptoms that had occurred three months before. Therapy failed toprove successful and gastroendoscopy was performed in March 2001 to reveal slightly reddish ventricularmucosa with normal rugal folds and a sessile, polypoid, grayish mass of rough surface located at the gastroe-sophageal junction. Histopathologic examination of polypoid mass samples revealed a vascular tumor cov-ered with squamous epithelium. The hallmarks of the tumor were numerous branching, slit-like capillarychannels with ‚staghorn™ appearance, and large gaping sinusoidal spaces enclosed within nests of ovoid cells.Vascular invasion, mitotic activity, giant cells and necrosis were not found. Immunohistochemical analysisshowed diffuse and strong reactivity for vimentin and focal, low or moderate reactivity for actin, S-100 andsmooth muscle actin. Proliferation index measured by PCNA and Ki-67 ranged from 2% to 13% (median11.2%) and from 5% to 18% (median 7.6%), respectively. A diagnosis of hemangiopericytoma with lowmalignant potential was made. Almost two years of the intervention, the patient is alive and free from anysigns of tumor spread.Key words: Esophageal neoplasms Œ pathology; Hemangiopericytoma Œ pathology; Hemangiopericytoma Œ immunochem-istry" @default.
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- W2190349574 date "2004-09-01" @default.
- W2190349574 modified "2023-09-24" @default.
- W2190349574 title "ESOPHAGEAL HEMANGIOPERICYTOMA OR HEMANGIOPERICYTOMA-LIKE TUMOR: A CASE REPORT AND REVIEW OF THE LITERATURE" @default.
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