FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2190647908> ?p ?o ?g. }

• W2190647908 endingPage "752" @default.
• W2190647908 startingPage "742" @default.
• W2190647908 abstract "Background Studies suggest an association between acute kidney injury (AKI) and long-term risk for chronic kidney disease (CKD), even following apparent renal recovery. Whether the pattern of renal recovery predicts kidney risk following AKI is unknown. Study Design Retrospective cohort. Setting & Participants Patients in the Veterans Health Administration in 2011 hospitalized (>24 hours) with at least 2 inpatient serum creatinine measurements, baseline estimated glomerular filtration rate > 60 mL/min/1.73 m2, and no diagnosis of end-stage renal disease or non−dialysis-dependent CKD: 17,049 (16.3%) with and 87,715 without AKI. Predictor Pattern of recovery to creatinine level within 0.3 mg/dL of baseline after AKI: within 2 days (fast), in 3 to 10 days (intermediate), and no recovery by 10 days (slow or unknown). Outcome CKD stage 3 or higher, defined as 2 outpatient estimated glomerular filtration rates < 60 mL/min/1.73 m2 at least 90 days apart or CKD diagnosis, dialysis therapy, or transplantation. Measurements Risk for CKD was modeled using modified Poisson regression and time to death-censored CKD was modeled using Cox proportional hazards regression, both stratified by AKI stage. Results Most patients’ AKI episodes were stage 1 (91%) and 71% recovered within 2 days. At 1 year, 18.2% had developed CKD (AKI, 31.8%; non-AKI, 15.5%; P < 0.001). In stage 1, the adjusted relative risk ratios for CKD stage 3 or higher were 1.43 (95% CI, 1.39-1.48), 2.00 (95% CI, 1.88-2.12), and 2.65 (95% CI, 2.51-2.80) for fast, intermediate, and slow/unknown recovery. A similar pattern was observed in subgroup analyses incorporating albuminuria and sensitivity analysis of death-censored time to CKD. Limitations Variable timing of follow-up and mostly male veteran cohort may limit generalizability. Conclusions Patients who develop AKI during a hospitalization are at substantial risk for the development of CKD by 1 year following hospitalization and timing of AKI recovery is a strong predictor, even for the mildest forms of AKI. Studies suggest an association between acute kidney injury (AKI) and long-term risk for chronic kidney disease (CKD), even following apparent renal recovery. Whether the pattern of renal recovery predicts kidney risk following AKI is unknown. Retrospective cohort. Patients in the Veterans Health Administration in 2011 hospitalized (>24 hours) with at least 2 inpatient serum creatinine measurements, baseline estimated glomerular filtration rate > 60 mL/min/1.73 m2, and no diagnosis of end-stage renal disease or non−dialysis-dependent CKD: 17,049 (16.3%) with and 87,715 without AKI. Pattern of recovery to creatinine level within 0.3 mg/dL of baseline after AKI: within 2 days (fast), in 3 to 10 days (intermediate), and no recovery by 10 days (slow or unknown). CKD stage 3 or higher, defined as 2 outpatient estimated glomerular filtration rates < 60 mL/min/1.73 m2 at least 90 days apart or CKD diagnosis, dialysis therapy, or transplantation. Risk for CKD was modeled using modified Poisson regression and time to death-censored CKD was modeled using Cox proportional hazards regression, both stratified by AKI stage. Most patients’ AKI episodes were stage 1 (91%) and 71% recovered within 2 days. At 1 year, 18.2% had developed CKD (AKI, 31.8%; non-AKI, 15.5%; P < 0.001). In stage 1, the adjusted relative risk ratios for CKD stage 3 or higher were 1.43 (95% CI, 1.39-1.48), 2.00 (95% CI, 1.88-2.12), and 2.65 (95% CI, 2.51-2.80) for fast, intermediate, and slow/unknown recovery. A similar pattern was observed in subgroup analyses incorporating albuminuria and sensitivity analysis of death-censored time to CKD. Variable timing of follow-up and mostly male veteran cohort may limit generalizability. Patients who develop AKI during a hospitalization are at substantial risk for the development of CKD by 1 year following hospitalization and timing of AKI recovery is a strong predictor, even for the mildest forms of AKI." @default.
• W2190647908 created "2016-06-24" @default.
• W2190647908 creator A5005022973 @default.
• W2190647908 creator A5006241342 @default.
• W2190647908 creator A5006265392 @default.
• W2190647908 creator A5007299590 @default.
• W2190647908 creator A5010020170 @default.
• W2190647908 creator A5011495488 @default.
• W2190647908 creator A5016758951 @default.
• W2190647908 creator A5020919570 @default.
• W2190647908 creator A5021339593 @default.
• W2190647908 creator A5023378337 @default.
• W2190647908 creator A5029169046 @default.
• W2190647908 creator A5029877293 @default.
• W2190647908 creator A5031187973 @default.
• W2190647908 creator A5037232419 @default.
• W2190647908 creator A5044278314 @default.
• W2190647908 creator A5044698181 @default.
• W2190647908 creator A5045832652 @default.
• W2190647908 creator A5047089859 @default.
• W2190647908 creator A5050973509 @default.
• W2190647908 creator A5052748532 @default.
• W2190647908 creator A5057706291 @default.
• W2190647908 creator A5062579436 @default.
• W2190647908 creator A5067842016 @default.
• W2190647908 creator A5071415825 @default.
• W2190647908 creator A5076142063 @default.
• W2190647908 creator A5077561870 @default.
• W2190647908 creator A5078385822 @default.
• W2190647908 creator A5078630017 @default.
• W2190647908 creator A5081078154 @default.
• W2190647908 creator A5081900637 @default.
• W2190647908 creator A5082554505 @default.
• W2190647908 creator A5086681800 @default.
• W2190647908 creator A5088829540 @default.
• W2190647908 date "2016-05-01" @default.
• W2190647908 modified "2023-10-11" @default.
• W2190647908 title "Acute Kidney Injury Recovery Pattern and Subsequent Risk of CKD: An Analysis of Veterans Health Administration Data" @default.
• W2190647908 cites W1987111346 @default.
• W2190647908 cites W1989028027 @default.
• W2190647908 cites W1999577714 @default.
• W2190647908 cites W2010522114 @default.
• W2190647908 cites W2013420788 @default.
• W2190647908 cites W2025627399 @default.
• W2190647908 cites W2033169788 @default.
• W2190647908 cites W2043488645 @default.
• W2190647908 cites W2047621580 @default.
• W2190647908 cites W2053521346 @default.
• W2190647908 cites W2059422023 @default.
• W2190647908 cites W2075596754 @default.
• W2190647908 cites W2077260857 @default.
• W2190647908 cites W2077967941 @default.
• W2190647908 cites W2079079821 @default.
• W2190647908 cites W2086420859 @default.
• W2190647908 cites W2099882810 @default.
• W2190647908 cites W2101752015 @default.
• W2190647908 cites W2112261155 @default.
• W2190647908 cites W2112669742 @default.
• W2190647908 cites W2116352783 @default.
• W2190647908 cites W2121827116 @default.
• W2190647908 cites W2125110911 @default.
• W2190647908 cites W2132716418 @default.
• W2190647908 cites W2133050759 @default.
• W2190647908 cites W2133460250 @default.
• W2190647908 cites W2135163018 @default.
• W2190647908 cites W2136709241 @default.
• W2190647908 cites W2142909616 @default.
• W2190647908 cites W2144026462 @default.
• W2190647908 cites W2145339507 @default.
• W2190647908 cites W2148001954 @default.
• W2190647908 cites W2149687213 @default.
• W2190647908 cites W2154156055 @default.
• W2190647908 cites W2155965977 @default.
• W2190647908 cites W2157364709 @default.
• W2190647908 cites W2161740609 @default.
• W2190647908 cites W2163900716 @default.
• W2190647908 cites W2164412910 @default.
• W2190647908 cites W2165041545 @default.
• W2190647908 cites W2167501720 @default.
• W2190647908 cites W2172095175 @default.
• W2190647908 cites W2582602949 @default.
• W2190647908 cites W2607031541 @default.
• W2190647908 doi "https://doi.org/10.1053/j.ajkd.2015.10.019" @default.
• W2190647908 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6837804" @default.
• W2190647908 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26690912" @default.
• W2190647908 hasPublicationYear "2016" @default.
• W2190647908 type Work @default.
• W2190647908 sameAs 2190647908 @default.
• W2190647908 citedByCount "272" @default.
• W2190647908 countsByYear W21906479082016 @default.
• W2190647908 countsByYear W21906479082017 @default.
• W2190647908 countsByYear W21906479082018 @default.
• W2190647908 countsByYear W21906479082019 @default.
• W2190647908 countsByYear W21906479082020 @default.
• W2190647908 countsByYear W21906479082021 @default.
• W2190647908 countsByYear W21906479082022 @default.
• W2190647908 countsByYear W21906479082023 @default.
• W2190647908 crossrefType "journal-article" @default.

• next