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• W2190699772 abstract "Abstract Background Patients with atrial fibrillation (AF) may benefit from undergoing concomitant interventions of left atrial catheter ablation and device occlusion of the left atrial appendage (LAA) as a two‐pronged strategy for rhythm control and stroke prevention. We report on the outcome of combined procedures in a single center case series over a 5‐year timeframe. Methods Ninety‐eight patients with non‐valvular AF and a mean CHA 2 DS 2 ‐VASc score 2.6±1.0 underwent either first time, or redo pulmonary vein isolation (PVI) procedures, followed by successful implant of a Watchman® device. Results All procedures were generally uncomplicated with a mean case time of 213±40 min. Complete LAA occlusion was achieved at initial implant in 92 (94%) patients. Satisfactory LAA occlusion was achieved in 100% of patients at 12 months, with a complete LAA occlusion rate of 86%. All patients discontinued oral anticoagulation. Persistent late peri‐device leaks were more frequently associated with device angulation or shoulder protrusion, and were associated with a significantly lower achieved device compression of 12±3% vs. 15±5% ( p <0.01) than complete occlusion. One ischemic stroke was recorded over a mean follow‐up time of 802±439 days. Twelve months' freedom from detectable AF was achieved in 77% of patients. Conclusions Combined procedures of catheter ablation for AF and Watchman® LAA implant appear to be feasible and safe, with excellent rates of LAA occlusion achieved and an observed stroke rate of 0.5% per year during mid‐term follow‐up. Incomplete occlusion was associated with lower achieved device compression and was more frequently associated with suboptimal device position." @default.
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• W2190699772 date "2015-12-08" @default.
• W2190699772 modified "2023-09-30" @default.
• W2190699772 title "Combined catheter ablation for atrial fibrillation and Watchman® left atrial appendage occlusion procedures: Five-year experience" @default.
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• W2190699772 doi "https://doi.org/10.1016/j.joa.2015.11.001" @default.
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