FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2191543670> ?p ?o ?g. }

• W2191543670 abstract "A proliferation-inducing ligand (APRIL) is a critical member of the tumor necrosis factor (TNF) superfamily, which is involved in immune regulation. In the present study, the cDNA of cat APRIL (cAPRIL) was successfully amplified. Sequence analysis showed that the open reading frame (ORF) of cAPRIL contains a putative furin protease cleavage site (R-R-K-R), a conserved putative N-glycosylation site (Asn(124)), and two conservative cysteine residues (Cys(196) and Cys(211)). Real-time quantitative PCR (qPCR) analysis revealed that cAPRIL could be detected in various tissues. The phylogenetic analysis and predicted three dimensional (3D) structure revealed that it is similar to its counterparts. The extracellular soluble domain of the cAPRIL (csAPRIL) fragment was cloned into the expression vector pET43.1a. SDS-PAGE and Western blotting analysis indicated a high-level expression of csAPRIL protein in Escherichia coli BL21 (DE3). MTT assays revealed that purified recombinant csAPRIL protein was able to stimulate proliferation of mouse B-cells. These findings indicate that cAPRIL plays an important role in proliferation of B-cells and provide the basis for investigation on the roles of APRIL in this important domestic species." @default.
• W2191543670 created "2016-06-24" @default.
• W2191543670 creator A5034282664 @default.
• W2191543670 creator A5060259824 @default.
• W2191543670 creator A5076017095 @default.
• W2191543670 creator A5084502351 @default.
• W2191543670 creator A5090949378 @default.
• W2191543670 creator A5091626667 @default.
• W2191543670 date "2015-10-20" @default.
• W2191543670 modified "2023-09-28" @default.
• W2191543670 title "Molecular Cloning, Recombinant Expression, and Funtional Characterization of APRIL (TNFSF13) in Cat (Felis catus)" @default.
• W2191543670 cites W1987131141 @default.
• W2191543670 cites W2007197620 @default.
• W2191543670 cites W2014173345 @default.
• W2191543670 cites W2026817557 @default.
• W2191543670 cites W2033296455 @default.
• W2191543670 cites W2048747213 @default.
• W2191543670 cites W2055816409 @default.
• W2191543670 cites W2061454749 @default.
• W2191543670 cites W2063258341 @default.
• W2191543670 cites W2070081543 @default.
• W2191543670 cites W2072380594 @default.
• W2191543670 cites W2105551999 @default.
• W2191543670 cites W2107277218 @default.
• W2191543670 cites W2109807697 @default.
• W2191543670 cites W2113737833 @default.
• W2191543670 cites W2115528666 @default.
• W2191543670 cites W2125121305 @default.
• W2191543670 cites W2130528267 @default.
• W2191543670 cites W2135640361 @default.
• W2191543670 cites W2166022914 @default.
• W2191543670 cites W4250393576 @default.
• W2191543670 doi "https://doi.org/10.1080/10495398.2014.977906" @default.
• W2191543670 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26485397" @default.
• W2191543670 hasPublicationYear "2015" @default.
• W2191543670 type Work @default.
• W2191543670 sameAs 2191543670 @default.
• W2191543670 citedByCount "0" @default.
• W2191543670 crossrefType "journal-article" @default.
• W2191543670 hasAuthorship W2191543670A5034282664 @default.
• W2191543670 hasAuthorship W2191543670A5060259824 @default.
• W2191543670 hasAuthorship W2191543670A5076017095 @default.
• W2191543670 hasAuthorship W2191543670A5084502351 @default.
• W2191543670 hasAuthorship W2191543670A5090949378 @default.
• W2191543670 hasAuthorship W2191543670A5091626667 @default.
• W2191543670 hasConcept C104317684 @default.
• W2191543670 hasConcept C121050878 @default.
• W2191543670 hasConcept C153911025 @default.
• W2191543670 hasConcept C167625842 @default.
• W2191543670 hasConcept C181199279 @default.
• W2191543670 hasConcept C187882448 @default.
• W2191543670 hasConcept C19924922 @default.
• W2191543670 hasConcept C199360897 @default.
• W2191543670 hasConcept C2777265534 @default.
• W2191543670 hasConcept C40767141 @default.
• W2191543670 hasConcept C41008148 @default.
• W2191543670 hasConcept C47289529 @default.
• W2191543670 hasConcept C54355233 @default.
• W2191543670 hasConcept C547475151 @default.
• W2191543670 hasConcept C55493867 @default.
• W2191543670 hasConcept C61053724 @default.
• W2191543670 hasConcept C85265743 @default.
• W2191543670 hasConcept C86803240 @default.
• W2191543670 hasConceptScore W2191543670C104317684 @default.
• W2191543670 hasConceptScore W2191543670C121050878 @default.
• W2191543670 hasConceptScore W2191543670C153911025 @default.
• W2191543670 hasConceptScore W2191543670C167625842 @default.
• W2191543670 hasConceptScore W2191543670C181199279 @default.
• W2191543670 hasConceptScore W2191543670C187882448 @default.
• W2191543670 hasConceptScore W2191543670C19924922 @default.
• W2191543670 hasConceptScore W2191543670C199360897 @default.
• W2191543670 hasConceptScore W2191543670C2777265534 @default.
• W2191543670 hasConceptScore W2191543670C40767141 @default.
• W2191543670 hasConceptScore W2191543670C41008148 @default.
• W2191543670 hasConceptScore W2191543670C47289529 @default.
• W2191543670 hasConceptScore W2191543670C54355233 @default.
• W2191543670 hasConceptScore W2191543670C547475151 @default.
• W2191543670 hasConceptScore W2191543670C55493867 @default.
• W2191543670 hasConceptScore W2191543670C61053724 @default.
• W2191543670 hasConceptScore W2191543670C85265743 @default.
• W2191543670 hasConceptScore W2191543670C86803240 @default.
• W2191543670 hasLocation W21915436701 @default.
• W2191543670 hasLocation W21915436702 @default.
• W2191543670 hasOpenAccess W2191543670 @default.
• W2191543670 hasPrimaryLocation W21915436701 @default.
• W2191543670 hasRelatedWork W1904335787 @default.
• W2191543670 hasRelatedWork W1979477515 @default.
• W2191543670 hasRelatedWork W1993654288 @default.
• W2191543670 hasRelatedWork W1996024570 @default.
• W2191543670 hasRelatedWork W1999890227 @default.
• W2191543670 hasRelatedWork W2009476325 @default.
• W2191543670 hasRelatedWork W2028576280 @default.
• W2191543670 hasRelatedWork W2033066292 @default.
• W2191543670 hasRelatedWork W2043859505 @default.
• W2191543670 hasRelatedWork W2046621497 @default.
• W2191543670 hasRelatedWork W2056073580 @default.
• W2191543670 hasRelatedWork W2063700109 @default.
• W2191543670 hasRelatedWork W2065957323 @default.
• W2191543670 hasRelatedWork W2079255606 @default.
• W2191543670 hasRelatedWork W2095319531 @default.

• next