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- W2191964184 abstract "Abstract In this paper we present a mathematical model for isovolumic left-ventricular pressure curves intended for applications in computer simulation models of the cardiovascular system. We chose a quadratic spline to individually account for the specific phases of isovolumic beats. Besides, we describe a method to identify subject specific isovolumic pressure curves based on measured physiological (non-isovolumic) pressure curves. Therefore, we used experimental data obtained from a trial on an anesthetized pig. Specifically, we investigated the effect of a preload reduction for a given contractile state on the isovolumic pressure curves. Towards validation of the proposed model we compared the predicted isovolumic pressure curve to data of real experimentally obtained isovolumic beats. Besides, a comparison to alternative isovolumic pressure curve identification approaches for a different application (estimating contractility by single-beat evaluation) is drawn." @default.
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- W2191964184 date "2015-01-01" @default.
- W2191964184 modified "2023-09-27" @default.
- W2191964184 title "Cardiac Modeling: Identification of Subject Specific Left-Ventricular Isovolumic Pressure Curves" @default.
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- W2191964184 doi "https://doi.org/10.1016/j.ifacol.2015.10.204" @default.
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