Matches in SemOpenAlex for { <https://semopenalex.org/work/W2192227492> ?p ?o ?g. }
- W2192227492 endingPage "1253" @default.
- W2192227492 startingPage "1243" @default.
- W2192227492 abstract "The aim was to investigate brain network function during working memory (WM) task performance in patients with uncomplicated mild traumatic brain injury (mTBI) in the sub-acute phase post-injury. We were particularly interested in differences between patients with (PCC-present) and without post-concussive complaints (PCC-absent). Fifty-two patients and twenty healthy controls (HCs) (matched for age, sex, education and handedness) were included. Two patient groups were created based on reported post-concussive complaints at two weeks post-injury: PCC-present (n = 32) and PCC-absent (n = 20). Functional MRI scans were made at approximately four weeks post-injury. Participants performed an n-back task consisting of three conditions (0-, 1- and 2-back) with increasing difficulty. General linear model analysis was performed to investigate activation patterns. Independent component analysis was used to identify brain networks. The frontal executive network (FEN), frontoparietal network (FPN) and default mode network (DMN) were selected for further analyses based on their highest task-relatedness. Task accuracy and reaction times were similar for patients with mTBI and HCs. During high WM load (2-vs.0-back contrast), mTBI patients exhibited lower activation within the medial prefrontal cortex compared to HCs. No differences were found between PCC-present and PCC-absent patients. Regarding network function, PCC-absent patients showed stronger deactivation of the DMN compared to PCC-present patients and HCs, especially during difficult task conditions. Furthermore, functional connectivity between the DMN and FEN was lower in PCC-absent patients compared to PCC-present patients. Interestingly, network function did not differ between PCC-present patients and HCs, suggesting that non-injury related factors may underlie post-concussive complaints after mTBI." @default.
- W2192227492 created "2016-06-24" @default.
- W2192227492 creator A5026029371 @default.
- W2192227492 creator A5034321427 @default.
- W2192227492 creator A5057999596 @default.
- W2192227492 creator A5064931931 @default.
- W2192227492 creator A5077428075 @default.
- W2192227492 creator A5079786665 @default.
- W2192227492 date "2015-12-14" @default.
- W2192227492 modified "2023-10-16" @default.
- W2192227492 title "Post-concussive complaints after mild traumatic brain injury associated with altered brain networks during working memory performance" @default.
- W2192227492 cites W1509900546 @default.
- W2192227492 cites W1531091112 @default.
- W2192227492 cites W1744998926 @default.
- W2192227492 cites W1845447069 @default.
- W2192227492 cites W1973741448 @default.
- W2192227492 cites W1978785608 @default.
- W2192227492 cites W1985327120 @default.
- W2192227492 cites W1987138256 @default.
- W2192227492 cites W2000697043 @default.
- W2192227492 cites W2002562224 @default.
- W2192227492 cites W2009898156 @default.
- W2192227492 cites W2011595299 @default.
- W2192227492 cites W2011782210 @default.
- W2192227492 cites W2017414981 @default.
- W2192227492 cites W2017688638 @default.
- W2192227492 cites W2021869533 @default.
- W2192227492 cites W2022853909 @default.
- W2192227492 cites W2029463069 @default.
- W2192227492 cites W2055345898 @default.
- W2192227492 cites W2061548360 @default.
- W2192227492 cites W2064076048 @default.
- W2192227492 cites W2070301140 @default.
- W2192227492 cites W2076750015 @default.
- W2192227492 cites W2076783616 @default.
- W2192227492 cites W2076796693 @default.
- W2192227492 cites W2080224340 @default.
- W2192227492 cites W2087404956 @default.
- W2192227492 cites W2089620859 @default.
- W2192227492 cites W2090020945 @default.
- W2192227492 cites W2090664364 @default.
- W2192227492 cites W2091420898 @default.
- W2192227492 cites W2102122784 @default.
- W2192227492 cites W2102669347 @default.
- W2192227492 cites W2104016179 @default.
- W2192227492 cites W2105876678 @default.
- W2192227492 cites W2108112020 @default.
- W2192227492 cites W2111066106 @default.
- W2192227492 cites W2112419450 @default.
- W2192227492 cites W2116658855 @default.
- W2192227492 cites W2117101773 @default.
- W2192227492 cites W2121533477 @default.
- W2192227492 cites W2127145783 @default.
- W2192227492 cites W2129624700 @default.
- W2192227492 cites W2130606996 @default.
- W2192227492 cites W2130654277 @default.
- W2192227492 cites W2133504285 @default.
- W2192227492 cites W2136435696 @default.
- W2192227492 cites W2138123424 @default.
- W2192227492 cites W2146083743 @default.
- W2192227492 cites W2147472624 @default.
- W2192227492 cites W2155276408 @default.
- W2192227492 cites W2161280329 @default.
- W2192227492 cites W2165114681 @default.
- W2192227492 cites W2166281097 @default.
- W2192227492 cites W2169793721 @default.
- W2192227492 cites W2172031239 @default.
- W2192227492 cites W2323955250 @default.
- W2192227492 cites W266634779 @default.
- W2192227492 doi "https://doi.org/10.1007/s11682-015-9489-y" @default.
- W2192227492 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5167217" @default.
- W2192227492 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26667033" @default.
- W2192227492 hasPublicationYear "2015" @default.
- W2192227492 type Work @default.
- W2192227492 sameAs 2192227492 @default.
- W2192227492 citedByCount "31" @default.
- W2192227492 countsByYear W21922274922016 @default.
- W2192227492 countsByYear W21922274922017 @default.
- W2192227492 countsByYear W21922274922018 @default.
- W2192227492 countsByYear W21922274922019 @default.
- W2192227492 countsByYear W21922274922020 @default.
- W2192227492 countsByYear W21922274922021 @default.
- W2192227492 countsByYear W21922274922022 @default.
- W2192227492 countsByYear W21922274922023 @default.
- W2192227492 crossrefType "journal-article" @default.
- W2192227492 hasAuthorship W2192227492A5026029371 @default.
- W2192227492 hasAuthorship W2192227492A5034321427 @default.
- W2192227492 hasAuthorship W2192227492A5057999596 @default.
- W2192227492 hasAuthorship W2192227492A5064931931 @default.
- W2192227492 hasAuthorship W2192227492A5077428075 @default.
- W2192227492 hasAuthorship W2192227492A5079786665 @default.
- W2192227492 hasBestOaLocation W21922274921 @default.
- W2192227492 hasConcept C118552586 @default.
- W2192227492 hasConcept C126322002 @default.
- W2192227492 hasConcept C141516989 @default.
- W2192227492 hasConcept C14216870 @default.
- W2192227492 hasConcept C15744967 @default.
- W2192227492 hasConcept C169760540 @default.