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• W2192962912 abstract "We reported a novel, non-optical technique to analyse and quantify the transportation of bacterial cells in paper-based microfluidics. This approach was based on real-time measurement of the microbial electricity production. Our device was designed to have three hydrophilic regions linked by a channel on a paper layer by patterning hydrophobic barriers in the paper. Each region came into contact with an anodic electrode layer which was stacked with a cathodic compartment through a proton exchange membrane. When bacterial cells were transported to each region by capillary force, the bacteria cells were promoted to adhere onto the anode and the cells completed their respiration by transferring the electrons to the anode. A conductive load connected the anode and cathode to complete the external circuit through which the electrons flowed. The protons generated by the anodic reactions passed through the proton exchange membrane and travelled to the cathode, where they combined with electrons in the reduction process. By measuring the current through the load, bacterial cells’ transportation through the channels in paper was quantitatively investigated according to the pore size of the paper. Further understanding was made by analysing electron microscope examination of the hydrophilic regions. This work will determine more efficient cell movement within a paper material by controlling the paper's microfluidic dimensions and pore size. It will also provide a quantitative understanding of the flow of large organisms for use in paper-based diagnostics." @default.
• W2192962912 created "2016-06-24" @default.
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• W2192962912 date "2016-12-01" @default.
• W2192962912 modified "2023-10-04" @default.
• W2192962912 title "Cellular flow in paper-based microfluidics" @default.
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• W2192962912 doi "https://doi.org/10.1016/j.snb.2015.11.127" @default.
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