Matches in SemOpenAlex for { <https://semopenalex.org/work/W2193048333> ?p ?o ?g. }
- W2193048333 endingPage "322" @default.
- W2193048333 startingPage "308" @default.
- W2193048333 abstract "Chronic spontaneous urticaria (CSU) is defined as persistent wheals, angioedema, or both lasting for >6 weeks due to known or unknown causes. Some epidemiological studies and case reports suggest that internal parasite infections (PI) can cause CSU. Here, we provide a systematic overview of published findings on the prevalence and relevance of PI in CSU and we discuss possible pathomechanisms. The prevalence of PI in CSU was investigated by 39 independent studies and comorbidity reportedly ranged from 0 to 75.4% (two-thirds of these studies reported infection rates of 10% or less). The prevalence of PI in adult and pediatric CSU patients ranged from 0% to 75.4% and from 0% to 37.8%, respectively. CSU patients were more often diagnosed with protozoa and had a significantly higher risk of toxocariasis seropositivity and Anisakis simplex sensitization when compared to healthy controls. Patients with chronic urticaria more frequently had seropositivity of fasciolosis, Anisakis simplex sensitization, and the presence of Blastocystis hominis allele 34 (ST3) as compared with control subjects. In 21 studies, efficacy of treatment with antiparasitic drugs ranged from 0 to 100% (35.7% of 269 CSU patients benefitted). In 9 (42.8%) of 21 studies, more than 50% of efficacy was observed. The reported rate of urticaria comorbidity in PI patients in 18 independent studies is 1–66.7%. Urticaria including CSU might be a quite common symptom of strongyloidiasis and blastocystosis. Pathogenic mechanisms in CSU due to PI may include specific IgE, Th2 cytokine skewing, eosinophils, activation of the complement, and the coagulation systems." @default.
- W2193048333 created "2016-06-24" @default.
- W2193048333 creator A5011138906 @default.
- W2193048333 creator A5029765923 @default.
- W2193048333 creator A5031874261 @default.
- W2193048333 creator A5046881136 @default.
- W2193048333 creator A5091156366 @default.
- W2193048333 date "2015-12-28" @default.
- W2193048333 modified "2023-10-10" @default.
- W2193048333 title "Chronic spontaneous urticaria and internal parasites - a systematic review" @default.
- W2193048333 cites W1504842648 @default.
- W2193048333 cites W1571914910 @default.
- W2193048333 cites W1598108561 @default.
- W2193048333 cites W1607794914 @default.
- W2193048333 cites W1670254077 @default.
- W2193048333 cites W1759977888 @default.
- W2193048333 cites W1773339068 @default.
- W2193048333 cites W1790629706 @default.
- W2193048333 cites W1895352358 @default.
- W2193048333 cites W1944621503 @default.
- W2193048333 cites W1951981193 @default.
- W2193048333 cites W1968988776 @default.
- W2193048333 cites W1971236733 @default.
- W2193048333 cites W1975792531 @default.
- W2193048333 cites W1977293145 @default.
- W2193048333 cites W1978185270 @default.
- W2193048333 cites W1982137939 @default.
- W2193048333 cites W1982312828 @default.
- W2193048333 cites W1982493133 @default.
- W2193048333 cites W1983312277 @default.
- W2193048333 cites W1985585453 @default.
- W2193048333 cites W1985696359 @default.
- W2193048333 cites W1986302589 @default.
- W2193048333 cites W1988649912 @default.
- W2193048333 cites W1992218749 @default.
- W2193048333 cites W1992828237 @default.
- W2193048333 cites W1995572931 @default.
- W2193048333 cites W1997887280 @default.
- W2193048333 cites W1999175450 @default.
- W2193048333 cites W2000225562 @default.
- W2193048333 cites W2000231297 @default.
- W2193048333 cites W2001325014 @default.
- W2193048333 cites W2002561997 @default.
- W2193048333 cites W2004690682 @default.
- W2193048333 cites W2005778769 @default.
- W2193048333 cites W2007026199 @default.
- W2193048333 cites W2007747800 @default.
- W2193048333 cites W2008419538 @default.
- W2193048333 cites W2008645602 @default.
- W2193048333 cites W2011671647 @default.
- W2193048333 cites W2017605267 @default.
- W2193048333 cites W2019239256 @default.
- W2193048333 cites W2019466068 @default.
- W2193048333 cites W2023110519 @default.
- W2193048333 cites W2023868269 @default.
- W2193048333 cites W2025258662 @default.
- W2193048333 cites W2027664945 @default.
- W2193048333 cites W2031842899 @default.
- W2193048333 cites W2033176949 @default.
- W2193048333 cites W2035931483 @default.
- W2193048333 cites W2036364274 @default.
- W2193048333 cites W2037128072 @default.
- W2193048333 cites W2040067540 @default.
- W2193048333 cites W2043524766 @default.
- W2193048333 cites W2044086932 @default.
- W2193048333 cites W2046439548 @default.
- W2193048333 cites W2050800572 @default.
- W2193048333 cites W2051037046 @default.
- W2193048333 cites W2056893677 @default.
- W2193048333 cites W2059040820 @default.
- W2193048333 cites W2060371599 @default.
- W2193048333 cites W2060548527 @default.
- W2193048333 cites W2063085762 @default.
- W2193048333 cites W2063634775 @default.
- W2193048333 cites W2068225657 @default.
- W2193048333 cites W2069724741 @default.
- W2193048333 cites W2071135646 @default.
- W2193048333 cites W2071299347 @default.
- W2193048333 cites W2072339607 @default.
- W2193048333 cites W2072670408 @default.
- W2193048333 cites W2073368400 @default.
- W2193048333 cites W2073934357 @default.
- W2193048333 cites W2074542352 @default.
- W2193048333 cites W2075001891 @default.
- W2193048333 cites W2078871741 @default.
- W2193048333 cites W2079551443 @default.
- W2193048333 cites W2081663722 @default.
- W2193048333 cites W208168060 @default.
- W2193048333 cites W2082683537 @default.
- W2193048333 cites W2085450451 @default.
- W2193048333 cites W2087000344 @default.
- W2193048333 cites W2090174990 @default.
- W2193048333 cites W2091157515 @default.
- W2193048333 cites W2091231396 @default.
- W2193048333 cites W2095027390 @default.
- W2193048333 cites W2095710479 @default.
- W2193048333 cites W2098742759 @default.
- W2193048333 cites W2101641061 @default.