Matches in SemOpenAlex for { <https://semopenalex.org/work/W2193684114> ?p ?o ?g. }
- W2193684114 endingPage "e0004225" @default.
- W2193684114 startingPage "e0004225" @default.
- W2193684114 abstract "Background Epidemiological studies carried out using culture or microscopy in most of the amoebiasis endemic developing countries, yielded confusing results since none of these could differentiate the pathogenic Entamoeba histolytica from the non-pathogenic Entamoeba dispar and Entamoeba moshkovskii. The Northeastern part of India is a hot spot of infection since the climatic conditions are most conducive for the infection and so far no systemic study has been carried out in this region. Methodology/Principal Findings Following a cross-sectional study designed during the period 2011–2014, a total of 1260 fecal samples collected from the Northeast Indian population were subjected to microscopy, fecal culture and a sensitive and specific DNA dot blot screening assay developed in our laboratory targeting the Entamoeba spp. Further species discrimination using PCR assay performed in microscopy, culture and DNA dot blot screening positive samples showed E. histolytica an overall prevalence rate of 11.1%, 8.0% and 13.7% respectively. In addition, infection rates of nonpathogenic E. dispar and E. moshkovskii were 11.8% (95% CI = 10.2, 13.8) and 7.8% (95% CI = 6.4, 9.4) respectively. The spatial distributions of infection were 18.2% (107/588) of Assam, 11.7% (23/197) of Manipur, 10.2% (21/207) of Meghalaya, and 8.2% (22/268) of Tripura states. Association study of the disease with demographic features suggested poor living condition (OR = 3.21; 95% CI = 1.83, 5.63), previous history of infection in family member (OR = 3.18; 95% CI = 2.09, 4.82) and unhygienic toilet facility (OR = 1.79; 95% CI = 1.28, 2.49) as significant risk factors for amoebiasis. Children in age group <15 yr, participants having lower levels of education, and daily laborers exhibited a higher infection rate. Conclusions/Significance Despite the importance of molecular diagnosis of amoebiasis, molecular epidemiological data based on a large sample size from endemic countries are rarely reported in the literature. Improved and faster method of diagnosis employed here to dissect out the pathogenic from the nonpathogenic species would help the clinicians to prescribe the appropriate anti-amoebic drug." @default.
- W2193684114 created "2016-06-24" @default.
- W2193684114 creator A5007428610 @default.
- W2193684114 creator A5021851545 @default.
- W2193684114 creator A5036180920 @default.
- W2193684114 creator A5088519448 @default.
- W2193684114 date "2015-12-03" @default.
- W2193684114 modified "2023-10-18" @default.
- W2193684114 title "Molecular Epidemiology of Amoebiasis: A Cross-Sectional Study among North East Indian Population" @default.
- W2193684114 cites W151093924 @default.
- W2193684114 cites W1975142565 @default.
- W2193684114 cites W1976531763 @default.
- W2193684114 cites W1980866693 @default.
- W2193684114 cites W1981744428 @default.
- W2193684114 cites W1992384346 @default.
- W2193684114 cites W2001450780 @default.
- W2193684114 cites W2006858319 @default.
- W2193684114 cites W2018767574 @default.
- W2193684114 cites W2019239256 @default.
- W2193684114 cites W2020564431 @default.
- W2193684114 cites W2021702997 @default.
- W2193684114 cites W2023270027 @default.
- W2193684114 cites W2031975140 @default.
- W2193684114 cites W2034072963 @default.
- W2193684114 cites W2034494554 @default.
- W2193684114 cites W2035067665 @default.
- W2193684114 cites W2035753511 @default.
- W2193684114 cites W2043319125 @default.
- W2193684114 cites W2051206389 @default.
- W2193684114 cites W2056963058 @default.
- W2193684114 cites W2063772430 @default.
- W2193684114 cites W2068499058 @default.
- W2193684114 cites W2074880433 @default.
- W2193684114 cites W2077103386 @default.
- W2193684114 cites W2080031069 @default.
- W2193684114 cites W2097726408 @default.
- W2193684114 cites W2106377506 @default.
- W2193684114 cites W2115573931 @default.
- W2193684114 cites W2120262254 @default.
- W2193684114 cites W2121127133 @default.
- W2193684114 cites W2125583989 @default.
- W2193684114 cites W2130221025 @default.
- W2193684114 cites W2130847820 @default.
- W2193684114 cites W2132360249 @default.
- W2193684114 cites W2133290730 @default.
- W2193684114 cites W2138633389 @default.
- W2193684114 cites W2144084878 @default.
- W2193684114 cites W2147194436 @default.
- W2193684114 cites W2148247121 @default.
- W2193684114 cites W2156127686 @default.
- W2193684114 cites W2160451704 @default.
- W2193684114 cites W2162649979 @default.
- W2193684114 cites W2163185216 @default.
- W2193684114 cites W2182123627 @default.
- W2193684114 cites W2195780479 @default.
- W2193684114 cites W2270566469 @default.
- W2193684114 cites W2338289138 @default.
- W2193684114 cites W2408766557 @default.
- W2193684114 cites W2409711003 @default.
- W2193684114 cites W2411061313 @default.
- W2193684114 cites W2414586897 @default.
- W2193684114 cites W2613511643 @default.
- W2193684114 cites W446438116 @default.
- W2193684114 cites W95918631 @default.
- W2193684114 doi "https://doi.org/10.1371/journal.pntd.0004225" @default.
- W2193684114 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4669114" @default.
- W2193684114 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26633890" @default.
- W2193684114 hasPublicationYear "2015" @default.
- W2193684114 type Work @default.
- W2193684114 sameAs 2193684114 @default.
- W2193684114 citedByCount "52" @default.
- W2193684114 countsByYear W21936841142015 @default.
- W2193684114 countsByYear W21936841142016 @default.
- W2193684114 countsByYear W21936841142017 @default.
- W2193684114 countsByYear W21936841142018 @default.
- W2193684114 countsByYear W21936841142019 @default.
- W2193684114 countsByYear W21936841142020 @default.
- W2193684114 countsByYear W21936841142021 @default.
- W2193684114 countsByYear W21936841142022 @default.
- W2193684114 countsByYear W21936841142023 @default.
- W2193684114 crossrefType "journal-article" @default.
- W2193684114 hasAuthorship W2193684114A5007428610 @default.
- W2193684114 hasAuthorship W2193684114A5021851545 @default.
- W2193684114 hasAuthorship W2193684114A5036180920 @default.
- W2193684114 hasAuthorship W2193684114A5088519448 @default.
- W2193684114 hasBestOaLocation W21936841141 @default.
- W2193684114 hasConcept C107130276 @default.
- W2193684114 hasConcept C142052008 @default.
- W2193684114 hasConcept C142724271 @default.
- W2193684114 hasConcept C190612196 @default.
- W2193684114 hasConcept C2776867272 @default.
- W2193684114 hasConcept C2777473665 @default.
- W2193684114 hasConcept C2778455923 @default.
- W2193684114 hasConcept C2779052163 @default.
- W2193684114 hasConcept C2908647359 @default.
- W2193684114 hasConcept C42972112 @default.
- W2193684114 hasConcept C61716771 @default.
- W2193684114 hasConcept C71924100 @default.