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• W2193868051 startingPage "133" @default.
• W2193868051 abstract "The pond snail Lymnaea provides highly valuable experimental models for top-down analyses of associative learning and memory. Using classical and operant conditioning paradigms, molecular mechanisms of consolidation, reconsolidation, extinction, and forgetting of associative memory have been investigated. Long-term memory (LTM) forms after multi-trial aversive conditioning but, unusually, also after single-trial reward conditioning (‘flash-bulb memory’). Molecular mechanisms of LTM involve highly conserved signaling pathways (nitric oxide/cyclic guanosine monophosphate/protein kinase G, cyclic adenosine monophosphate/protein kinase A, and mitogen-activated protein kinase), transcriptional regulation of gene expression by cAMP response element binding protein and CCAAT/enhancer binding protein, and new protein synthesis. Importantly, a number of molecular processes involved in LTM have been traced from the behavioral level to single identified neurons." @default.
• W2193868051 created "2016-06-24" @default.
• W2193868051 creator A5037479524 @default.
• W2193868051 date "2008-01-01" @default.
• W2193868051 modified "2023-10-18" @default.
• W2193868051 title "Molecular Mechanism of Associative Learning in Lymnaea" @default.
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