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- W2194036494 abstract "Chronic inflammatory diseases are on the rise in the Westernized world. This rise has been correlated to a range of environmental factors, such as birth mode, rural versus urban living conditions, and use of antibiotics. Such environmental factors also influence early life gut microbiota (GM) colonization and maturation--and there is growing evidence that the negative effects of these factors on human health are mediated via GM alterations. Colonization of the gut initiates priming of the immune system from birth, driving tolerance towards non-harmful microorganisms and dietary antigens and proper reactions towards invading pathogens. This early colonization is crucial for the establishment of a healthy GM, and throughout life the balanced interaction of GM and immune system is a key element in maintaining health. An immune system out of balance increases the risk for later life inflammatory diseases. Animal models are indispensable in the studies of GM influence on disease mechanisms and progression, and focus points include studies of GM modification during pregnancy and perinatal life. Here, we present an overview of animal studies which have contributed to our understanding of GM functions in early life and how alterations affect risk and expression of certain inflammatory diseases with juvenile onset, including interventions, such as birth mode, antibiotics, and probiotics." @default.
- W2194036494 created "2016-06-24" @default.
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- W2194036494 date "2015-12-01" @default.
- W2194036494 modified "2023-10-18" @default.
- W2194036494 title "The influence of the young microbiome on inflammatory diseases-Lessons from animal studies" @default.
- W2194036494 cites W1492946553 @default.
- W2194036494 cites W1552915946 @default.
- W2194036494 cites W1596258860 @default.
- W2194036494 cites W1730634764 @default.
- W2194036494 cites W1766627147 @default.
- W2194036494 cites W1908000692 @default.
- W2194036494 cites W1964924481 @default.
- W2194036494 cites W1970140945 @default.
- W2194036494 cites W1970777915 @default.
- W2194036494 cites W1973919624 @default.
- W2194036494 cites W1975006117 @default.
- W2194036494 cites W1975696541 @default.
- W2194036494 cites W1981296136 @default.
- W2194036494 cites W1983936313 @default.
- W2194036494 cites W1988066089 @default.
- W2194036494 cites W1990873894 @default.
- W2194036494 cites W1998180461 @default.
- W2194036494 cites W1998992617 @default.
- W2194036494 cites W1999500451 @default.
- W2194036494 cites W1999537838 @default.
- W2194036494 cites W2001897420 @default.
- W2194036494 cites W2002553376 @default.
- W2194036494 cites W2002764130 @default.
- W2194036494 cites W2002797131 @default.
- W2194036494 cites W2003836872 @default.
- W2194036494 cites W2003988648 @default.
- W2194036494 cites W2004608617 @default.
- W2194036494 cites W2004774344 @default.
- W2194036494 cites W2007910255 @default.
- W2194036494 cites W2011333102 @default.
- W2194036494 cites W2014071845 @default.
- W2194036494 cites W2014676683 @default.
- W2194036494 cites W2017850486 @default.
- W2194036494 cites W2018826444 @default.
- W2194036494 cites W2020016349 @default.
- W2194036494 cites W2020913417 @default.
- W2194036494 cites W2023506796 @default.
- W2194036494 cites W2024285987 @default.
- W2194036494 cites W2024392143 @default.
- W2194036494 cites W2026045997 @default.
- W2194036494 cites W2031502524 @default.
- W2194036494 cites W2032318494 @default.
- W2194036494 cites W2033587400 @default.
- W2194036494 cites W2034082915 @default.
- W2194036494 cites W2035831689 @default.
- W2194036494 cites W2037638312 @default.
- W2194036494 cites W2037803098 @default.
- W2194036494 cites W2042369630 @default.
- W2194036494 cites W2044593828 @default.
- W2194036494 cites W2051563029 @default.
- W2194036494 cites W2055388500 @default.
- W2194036494 cites W2055750232 @default.
- W2194036494 cites W2058945509 @default.
- W2194036494 cites W2059835573 @default.
- W2194036494 cites W2061049727 @default.
- W2194036494 cites W2065149803 @default.
- W2194036494 cites W2066989460 @default.
- W2194036494 cites W2068031380 @default.
- W2194036494 cites W2069735156 @default.
- W2194036494 cites W2071230993 @default.
- W2194036494 cites W2071254556 @default.
- W2194036494 cites W2072064533 @default.
- W2194036494 cites W2073544687 @default.
- W2194036494 cites W2078621117 @default.
- W2194036494 cites W2081319466 @default.
- W2194036494 cites W2082884465 @default.
- W2194036494 cites W2085818612 @default.
- W2194036494 cites W2091186163 @default.
- W2194036494 cites W2091918308 @default.
- W2194036494 cites W2093506863 @default.
- W2194036494 cites W2096891797 @default.
- W2194036494 cites W2098425104 @default.
- W2194036494 cites W2098762803 @default.
- W2194036494 cites W2100357887 @default.
- W2194036494 cites W2101654035 @default.
- W2194036494 cites W2101798908 @default.
- W2194036494 cites W2103847109 @default.
- W2194036494 cites W2106355313 @default.
- W2194036494 cites W2107209401 @default.
- W2194036494 cites W2111947288 @default.
- W2194036494 cites W2112890441 @default.
- W2194036494 cites W2115747701 @default.
- W2194036494 cites W2122623396 @default.
- W2194036494 cites W2123895022 @default.
- W2194036494 cites W2124536003 @default.
- W2194036494 cites W2125826412 @default.
- W2194036494 cites W2128029492 @default.
- W2194036494 cites W2128147943 @default.