Matches in SemOpenAlex for { <https://semopenalex.org/work/W219417341> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W219417341 abstract "Abstract : A phase I/II clinical trial evaluating the feasibility, safety, and clinical efficacy of adoptive cellular therapy combined with dendritic cell (DC) vaccination targeting recurrent medulloblastoma and PNETs was opened for enrollment at Duke University Medical Center during the previous funding period (Year 1). DC generation and T cell expansion from archived post-induction chemotherapy specimens from five patients with medulloblastoma was attempted and mature RNA-pulsed DCs were successfully generated from 3 of 5 specimens and successful T cell expansion was achieved from these samples. Limitations in the yield of DCs and T cells from these specimens prompted a modification to the protocol to collect a leukapheresis sample prior to induction chemotherapy. A web-based clinical database for patient and laboratory data storage (Oracle Clinical) has been created by the Duke Comprehensive Cancer Center Bioinformatics team and is undergoing final beta testing and personnel training for release. Advertising efforts have increased awareness and recent referrals to the study protocol. Two subjects have been enrolled on the protocol, one removed due to final pathology other than medulloblastoma/PNET, and the other scheduled for surgical resection next week. Two additional subjects are currently undergoing screening for enrollment." @default.
- W219417341 created "2016-06-24" @default.
- W219417341 creator A5087959258 @default.
- W219417341 date "2011-04-01" @default.
- W219417341 modified "2023-09-27" @default.
- W219417341 title "Adoptive Cellular Therapy Targeting Recurrent Pediatric Brain Cancers During Hematopoietic Recovery from High-Dose Chemotherapy" @default.
- W219417341 hasPublicationYear "2011" @default.
- W219417341 type Work @default.
- W219417341 sameAs 219417341 @default.
- W219417341 citedByCount "0" @default.
- W219417341 crossrefType "journal-article" @default.
- W219417341 hasAuthorship W219417341A5087959258 @default.
- W219417341 hasConcept C10205521 @default.
- W219417341 hasConcept C126322002 @default.
- W219417341 hasConcept C141071460 @default.
- W219417341 hasConcept C142724271 @default.
- W219417341 hasConcept C143998085 @default.
- W219417341 hasConcept C2776611710 @default.
- W219417341 hasConcept C2776694085 @default.
- W219417341 hasConcept C2777371436 @default.
- W219417341 hasConcept C2780789225 @default.
- W219417341 hasConcept C28328180 @default.
- W219417341 hasConcept C535046627 @default.
- W219417341 hasConcept C54355233 @default.
- W219417341 hasConcept C71924100 @default.
- W219417341 hasConcept C86803240 @default.
- W219417341 hasConceptScore W219417341C10205521 @default.
- W219417341 hasConceptScore W219417341C126322002 @default.
- W219417341 hasConceptScore W219417341C141071460 @default.
- W219417341 hasConceptScore W219417341C142724271 @default.
- W219417341 hasConceptScore W219417341C143998085 @default.
- W219417341 hasConceptScore W219417341C2776611710 @default.
- W219417341 hasConceptScore W219417341C2776694085 @default.
- W219417341 hasConceptScore W219417341C2777371436 @default.
- W219417341 hasConceptScore W219417341C2780789225 @default.
- W219417341 hasConceptScore W219417341C28328180 @default.
- W219417341 hasConceptScore W219417341C535046627 @default.
- W219417341 hasConceptScore W219417341C54355233 @default.
- W219417341 hasConceptScore W219417341C71924100 @default.
- W219417341 hasConceptScore W219417341C86803240 @default.
- W219417341 hasLocation W2194173411 @default.
- W219417341 hasOpenAccess W219417341 @default.
- W219417341 hasPrimaryLocation W2194173411 @default.
- W219417341 hasRelatedWork W1974159927 @default.
- W219417341 hasRelatedWork W2012112188 @default.
- W219417341 hasRelatedWork W2118980621 @default.
- W219417341 hasRelatedWork W2122002540 @default.
- W219417341 hasRelatedWork W2122521718 @default.
- W219417341 hasRelatedWork W2128961069 @default.
- W219417341 hasRelatedWork W2175339761 @default.
- W219417341 hasRelatedWork W2222860631 @default.
- W219417341 hasRelatedWork W2335652984 @default.
- W219417341 hasRelatedWork W2337771206 @default.
- W219417341 hasRelatedWork W2341931364 @default.
- W219417341 hasRelatedWork W2475921979 @default.
- W219417341 hasRelatedWork W2604767721 @default.
- W219417341 hasRelatedWork W2805800267 @default.
- W219417341 hasRelatedWork W2807350303 @default.
- W219417341 hasRelatedWork W2948008134 @default.
- W219417341 hasRelatedWork W2999282261 @default.
- W219417341 hasRelatedWork W3103488181 @default.
- W219417341 hasRelatedWork W3101860855 @default.
- W219417341 hasRelatedWork W3149851393 @default.
- W219417341 isParatext "false" @default.
- W219417341 isRetracted "false" @default.
- W219417341 magId "219417341" @default.
- W219417341 workType "article" @default.