Matches in SemOpenAlex for { <https://semopenalex.org/work/W2194350385> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2194350385 endingPage "220" @default.
- W2194350385 startingPage "215" @default.
- W2194350385 abstract "The Caco-2 cells have been recognized as effective tools to be applied to imitate the drug absorption in human intestine for the transport of drug. In this study, Caco-2 cell monolayer model was used to study compatibility of the transport of the Veratrum alkaloids in different proportions with Panax ginseng. A specific ultra-high performance liquid chromatographic-electrospray ionization-mass spectrometric (UPLC-ESI-MS) method is developed for the semi-quantitative determination of Veratrum alkaloids on intestinal transport with berberine as internal standard (IS). In the Caco-2 model constructed, three influencing factors are investigated, including time, concentration and recovery rates of the Veratrum alkaloids during the uptake from AP (apical side) to BL (basolateral side). The results suggest that the flux of Veratrum alkaloids is time dependent and concentration dependent. And the absorption of all eight Veratrum alkaloids increase after compatibility with Panax ginseng compared to the single Veratrum nigrum extraction. This research was studied from the perspective of intestinal absorption by the UPLC-ESI-MS method. This method was successfully applied to transport studies of the Veratrum alkaloids and the interaction mechanism between Veratrum nigrum and Panax ginseng." @default.
- W2194350385 created "2016-06-24" @default.
- W2194350385 creator A5000698319 @default.
- W2194350385 creator A5008391277 @default.
- W2194350385 creator A5025993925 @default.
- W2194350385 creator A5058234160 @default.
- W2194350385 creator A5078295102 @default.
- W2194350385 creator A5088872065 @default.
- W2194350385 date "2016-02-01" @default.
- W2194350385 modified "2023-10-17" @default.
- W2194350385 title "Study on intestinal transport of Veratrum alkaloids compatible with Panax ginseng across the Caco-2 cell monolayer model by UPLC-ESI-MS method" @default.
- W2194350385 cites W1580684536 @default.
- W2194350385 cites W1973244809 @default.
- W2194350385 cites W1994466668 @default.
- W2194350385 cites W2028273867 @default.
- W2194350385 cites W2034333719 @default.
- W2194350385 cites W2097619128 @default.
- W2194350385 cites W2099358427 @default.
- W2194350385 cites W2120099165 @default.
- W2194350385 cites W2126097862 @default.
- W2194350385 cites W2126959080 @default.
- W2194350385 cites W2352027361 @default.
- W2194350385 doi "https://doi.org/10.1016/j.cclet.2015.10.003" @default.
- W2194350385 hasPublicationYear "2016" @default.
- W2194350385 type Work @default.
- W2194350385 sameAs 2194350385 @default.
- W2194350385 citedByCount "6" @default.
- W2194350385 countsByYear W21943503852017 @default.
- W2194350385 countsByYear W21943503852018 @default.
- W2194350385 countsByYear W21943503852020 @default.
- W2194350385 countsByYear W21943503852021 @default.
- W2194350385 countsByYear W21943503852022 @default.
- W2194350385 crossrefType "journal-article" @default.
- W2194350385 hasAuthorship W2194350385A5000698319 @default.
- W2194350385 hasAuthorship W2194350385A5008391277 @default.
- W2194350385 hasAuthorship W2194350385A5025993925 @default.
- W2194350385 hasAuthorship W2194350385A5058234160 @default.
- W2194350385 hasAuthorship W2194350385A5078295102 @default.
- W2194350385 hasAuthorship W2194350385A5088872065 @default.
- W2194350385 hasConcept C142724271 @default.
- W2194350385 hasConcept C1491633281 @default.
- W2194350385 hasConcept C162356407 @default.
- W2194350385 hasConcept C185592680 @default.
- W2194350385 hasConcept C193176779 @default.
- W2194350385 hasConcept C204787440 @default.
- W2194350385 hasConcept C2776539398 @default.
- W2194350385 hasConcept C2779232237 @default.
- W2194350385 hasConcept C2780116568 @default.
- W2194350385 hasConcept C40684141 @default.
- W2194350385 hasConcept C43617362 @default.
- W2194350385 hasConcept C55493867 @default.
- W2194350385 hasConcept C556039675 @default.
- W2194350385 hasConcept C71924100 @default.
- W2194350385 hasConceptScore W2194350385C142724271 @default.
- W2194350385 hasConceptScore W2194350385C1491633281 @default.
- W2194350385 hasConceptScore W2194350385C162356407 @default.
- W2194350385 hasConceptScore W2194350385C185592680 @default.
- W2194350385 hasConceptScore W2194350385C193176779 @default.
- W2194350385 hasConceptScore W2194350385C204787440 @default.
- W2194350385 hasConceptScore W2194350385C2776539398 @default.
- W2194350385 hasConceptScore W2194350385C2779232237 @default.
- W2194350385 hasConceptScore W2194350385C2780116568 @default.
- W2194350385 hasConceptScore W2194350385C40684141 @default.
- W2194350385 hasConceptScore W2194350385C43617362 @default.
- W2194350385 hasConceptScore W2194350385C55493867 @default.
- W2194350385 hasConceptScore W2194350385C556039675 @default.
- W2194350385 hasConceptScore W2194350385C71924100 @default.
- W2194350385 hasFunder F4320321001 @default.
- W2194350385 hasFunder F4320335777 @default.
- W2194350385 hasIssue "2" @default.
- W2194350385 hasLocation W21943503851 @default.
- W2194350385 hasOpenAccess W2194350385 @default.
- W2194350385 hasPrimaryLocation W21943503851 @default.
- W2194350385 hasRelatedWork W1601651444 @default.
- W2194350385 hasRelatedWork W1967316171 @default.
- W2194350385 hasRelatedWork W1982395256 @default.
- W2194350385 hasRelatedWork W2031713231 @default.
- W2194350385 hasRelatedWork W2349794035 @default.
- W2194350385 hasRelatedWork W2356195080 @default.
- W2194350385 hasRelatedWork W2356727060 @default.
- W2194350385 hasRelatedWork W2363731782 @default.
- W2194350385 hasRelatedWork W2385390334 @default.
- W2194350385 hasRelatedWork W4239232887 @default.
- W2194350385 hasVolume "27" @default.
- W2194350385 isParatext "false" @default.
- W2194350385 isRetracted "false" @default.
- W2194350385 magId "2194350385" @default.
- W2194350385 workType "article" @default.