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- W2194664614 abstract "Three rhythmic movements, breathing, walking, and chewing, are considered from the perspective of the emerging factors that control their coordination. This takes us beyond the concept of a core excitatory kernel and into the common principles that govern the interaction between components of the neural networks that must be orchestrated properly to produce meaningful movement beyond the production of the basic rhythm. We focus on the role of neuromodulators, especially 5-hydroxytryptamine (5-HT), in the production of coordinated breathing, walking, and chewing, and we review the evidence that at least in the case of breathing and walking, 5-HT input to the CPGs acts through the selection of inhibitory interneurons that are essential for coordination. We review data from recently developed mouse models that offer insight into the contributions of inhibitory coordinating neurons, including the development of a new model that has allowed the revelation that there are glycinergic pacemaker neurons that likely contribute to the production of the respiratory rhythm. Perhaps walking and chewing will not be far behind." @default.
- W2194664614 created "2016-06-24" @default.
- W2194664614 creator A5026679041 @default.
- W2194664614 creator A5060174174 @default.
- W2194664614 date "2011-01-01" @default.
- W2194664614 modified "2023-09-29" @default.
- W2194664614 title "Modulation of rhythmic movement" @default.
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- W2194664614 doi "https://doi.org/10.1016/b978-0-444-53825-3.00017-6" @default.
- W2194664614 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21333810" @default.
- W2194664614 hasPublicationYear "2011" @default.
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