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• W2196731158 startingPage "R484" @default.
• W2196731158 abstract "The current study addressed whether physical activity can buffer stress-induced behavioral depression and immunosuppression. Adult, male Sprague-Dawley rats were housed with either a mobile (physically active) or immobile (sedentary) running wheel and exposed to either stress (inescapable tail shock) or no stress (home cage control). Voluntary wheel running began 4 wk before stressor exposure. Immediately before stress, all rats were administered an intraperitoneal injection of keyhole limpet hemocyanin (KLH; 200 microg), and anti-KLH Ig was measured weekly for 4 wk using ELISA. Prior physical activity reduced the stress-induced behavioral depression and prevented the stress-induced suppression of anti-KLH IgM and IgG(2a) antibodies. Anti-KLH IgG(1) was stress insensitive. These data suggest that physical activity can buffer the negative impact of stress on behavior and acquired immune function." @default.
• W2196731158 created "2016-06-24" @default.
• W2196731158 creator A5014748156 @default.
• W2196731158 creator A5078597412 @default.
• W2196731158 date "2001-08-01" @default.
• W2196731158 modified "2023-10-16" @default.
• W2196731158 title "Voluntary physical activity prevents stress-induced behavioral depression and anti-KLH antibody suppression" @default.
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• W2196731158 doi "https://doi.org/10.1152/ajpregu.2001.281.2.r484" @default.
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