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- W2197366979 abstract "In our preliminary radiopharmaceutical study, 153Gd-DTPA-Folate has been successfully prepared, and tested for its bio-distribution. This continuing study is aimed at synthesizing and characterizing Gd-DTPA-Folate. The synthesis was started with the preparation of a derivative of folic acid, EDA-Folate, which was subsequently reacted with DTPA-Dianhydride to form DTPA-Folate. Finally, DTPA-Folate was reacted with Gd3+ to result in Gd-DTPA-Folate, on a 0.1-10 gram scale, with a yield of 97.2%. Experimental data collected from characterization of purified synthetic products using ultraviolet, infrared, and mass spectroscopy, indicated the formation of Gd-O and Gd-N bonds leading to the formation of Gd-DTPA-Folate molecule." @default.
- W2197366979 created "2016-06-24" @default.
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- W2197366979 date "2015-01-01" @default.
- W2197366979 modified "2023-10-06" @default.
- W2197366979 title "Synthesis and Characterization of Gadolinium Diethylenetriamine Pentaacetate-Folate" @default.
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- W2197366979 doi "https://doi.org/10.1016/j.proche.2015.12.128" @default.
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