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• W2197605564 abstract "Exit of thiomethylgalactoside (TMG) from preloaded cells induced the accumulation of proline. Likewise, proline exit stimulated TMG accumulation. Since a proton ionophore (carbonyl-cyanide-m-chlorophenylhydrazone) abolished these effects, a proton-motive force was implicated as the “intermediate” in the coupling reaction. The evidence suggests that the exit of TMG resulted in proton exit, which produced either a membrane potential (inside negative) or a pH gradient (outside acid) or both. This inwardly directed protonmotive force provided the energy for proline entry and accumulation. Thus the energy coupling was not via a common transport protein but by proton movements which coupled the two separate H+-dependent transport processes." @default.
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• W2197605564 date "1978-01-01" @default.
• W2197605564 modified "2023-09-27" @default.
• W2197605564 title "A Novel Type of Coupling Between Proline and Galactoside Transport in<i>Escherichia coli</i>" @default.
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• W2197605564 doi "https://doi.org/10.3109/09687687809064159" @default.
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