Matches in SemOpenAlex for { <https://semopenalex.org/work/W2197835595> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2197835595 endingPage "32" @default.
- W2197835595 startingPage "MT127" @default.
- W2197835595 abstract "This insight review introduces the new concepts, theories, technology, instruments, frontier issues, and key strategies of ADMET (absorption, distribution, metabolism, elimination, and toxicity) biosensors, from the fermi to the quantum levels. Information about ADMET, originating from one author's invention, a patented pharmacotherapy for rescuing cardio-cerebral vascular stunning and regulating vascular endothelial growth-factor signaling at the post-genomic level, can be detected by a new generation of ADMET biosensor. This is a single-cell/single-molecule field-effect transistor (FET) hybrid system, where single molecules or single cells are assembled at the FET surface in a high density array manner via complementary metal-oxide-semiconductor (CMOS)-compatible technologies. Within a given nanometer distance, ADMET-mediated oxidation-reduction (redox) potentials, electrochemistry responses, and electron transfer processes can be simultaneously and directly probed by the gates of field-effect transistor arrays. The nanometer details of the functional coupling principles and characterization technologies of DNA single-molecule/single-cell FETs, as well as the design of lab-on-a-chip instruments, are indicated. Four frontier issues and key strategies are elucidated in detail. This can lead to innovative technology for high-throughout screening of labs-on-chips to resolve the pharmaceutical industry's current bottleneck via novel, FET-based drug discovery and single-molecule/single-cell screening methods, which can bring about a pharmaceutical industry revolution in the 21st century." @default.
- W2197835595 created "2016-06-24" @default.
- W2197835595 creator A5074603734 @default.
- W2197835595 creator A5080458134 @default.
- W2197835595 date "2004-12-01" @default.
- W2197835595 modified "2023-09-23" @default.
- W2197835595 title "ADMET biosensors: up-to-date issues and strategies." @default.
- W2197835595 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15567991" @default.
- W2197835595 hasPublicationYear "2004" @default.
- W2197835595 type Work @default.
- W2197835595 sameAs 2197835595 @default.
- W2197835595 citedByCount "3" @default.
- W2197835595 countsByYear W21978355952015 @default.
- W2197835595 crossrefType "journal-article" @default.
- W2197835595 hasAuthorship W2197835595A5074603734 @default.
- W2197835595 hasAuthorship W2197835595A5080458134 @default.
- W2197835595 hasConcept C119599485 @default.
- W2197835595 hasConcept C127413603 @default.
- W2197835595 hasConcept C145598152 @default.
- W2197835595 hasConcept C149635348 @default.
- W2197835595 hasConcept C160756335 @default.
- W2197835595 hasConcept C165801399 @default.
- W2197835595 hasConcept C171250308 @default.
- W2197835595 hasConcept C172385210 @default.
- W2197835595 hasConcept C185592680 @default.
- W2197835595 hasConcept C192562407 @default.
- W2197835595 hasConcept C2780513914 @default.
- W2197835595 hasConcept C41008148 @default.
- W2197835595 hasConcept C46362747 @default.
- W2197835595 hasConcept C49040817 @default.
- W2197835595 hasConcept C55493867 @default.
- W2197835595 hasConcept C74187038 @default.
- W2197835595 hasConceptScore W2197835595C119599485 @default.
- W2197835595 hasConceptScore W2197835595C127413603 @default.
- W2197835595 hasConceptScore W2197835595C145598152 @default.
- W2197835595 hasConceptScore W2197835595C149635348 @default.
- W2197835595 hasConceptScore W2197835595C160756335 @default.
- W2197835595 hasConceptScore W2197835595C165801399 @default.
- W2197835595 hasConceptScore W2197835595C171250308 @default.
- W2197835595 hasConceptScore W2197835595C172385210 @default.
- W2197835595 hasConceptScore W2197835595C185592680 @default.
- W2197835595 hasConceptScore W2197835595C192562407 @default.
- W2197835595 hasConceptScore W2197835595C2780513914 @default.
- W2197835595 hasConceptScore W2197835595C41008148 @default.
- W2197835595 hasConceptScore W2197835595C46362747 @default.
- W2197835595 hasConceptScore W2197835595C49040817 @default.
- W2197835595 hasConceptScore W2197835595C55493867 @default.
- W2197835595 hasConceptScore W2197835595C74187038 @default.
- W2197835595 hasIssue "12" @default.
- W2197835595 hasLocation W21978355951 @default.
- W2197835595 hasOpenAccess W2197835595 @default.
- W2197835595 hasPrimaryLocation W21978355951 @default.
- W2197835595 hasRelatedWork W1567325000 @default.
- W2197835595 hasRelatedWork W2017202504 @default.
- W2197835595 hasRelatedWork W2094223453 @default.
- W2197835595 hasRelatedWork W2104914575 @default.
- W2197835595 hasRelatedWork W2117951316 @default.
- W2197835595 hasRelatedWork W2126632661 @default.
- W2197835595 hasRelatedWork W2317611551 @default.
- W2197835595 hasRelatedWork W2379778543 @default.
- W2197835595 hasRelatedWork W2516702102 @default.
- W2197835595 hasRelatedWork W2520827147 @default.
- W2197835595 hasRelatedWork W2772444925 @default.
- W2197835595 hasRelatedWork W2953397122 @default.
- W2197835595 hasRelatedWork W2976050857 @default.
- W2197835595 hasRelatedWork W2982799947 @default.
- W2197835595 hasRelatedWork W2994146441 @default.
- W2197835595 hasRelatedWork W3010846855 @default.
- W2197835595 hasRelatedWork W3091881029 @default.
- W2197835595 hasRelatedWork W35363013 @default.
- W2197835595 hasRelatedWork W409677737 @default.
- W2197835595 hasRelatedWork W870904012 @default.
- W2197835595 hasVolume "10" @default.
- W2197835595 isParatext "false" @default.
- W2197835595 isRetracted "false" @default.
- W2197835595 magId "2197835595" @default.
- W2197835595 workType "article" @default.