Matches in SemOpenAlex for { <https://semopenalex.org/work/W2197903979> ?p ?o ?g. }
- W2197903979 endingPage "115" @default.
- W2197903979 startingPage "91" @default.
- W2197903979 abstract "For more than 100 years it has been known that gastric acid secretion is not the only but an essential causative factor in the pathogenesis of acid-related diseases. Thus reduction of acid secretion became a major therapeutic goal. For most of this century, effective acid reduction could be achieved only by surgery (gastric resection and vagotomy). The introduction of potent inhibitors of acid secretion, that is the H2-receptor blocking agent cimetidine and its analogues in the late seventies and the even more potent proton pump inhibitor (PPI) omeprazole and its analogues in the late eighties have revolutionized therapy. Surgery became superfluous for benign oesophagogastric diseases, except in case of perforation or haemorrhage. However, soon after the introduction of the H2-receptor blockers concern was expressed about the risk of hypochlorhydria or achlorhydria. This concern originates in the conviction that gastric acid is needed for normal life and that achlorhydria will cause serious problems. But do we really know how much gastric acid we need?" @default.
- W2197903979 created "2016-06-24" @default.
- W2197903979 creator A5006244909 @default.
- W2197903979 date "1999-01-01" @default.
- W2197903979 modified "2023-09-25" @default.
- W2197903979 title "Consequences of gastric acid inhibition in man" @default.
- W2197903979 cites W1545424283 @default.
- W2197903979 cites W1575226998 @default.
- W2197903979 cites W1676960647 @default.
- W2197903979 cites W1773010324 @default.
- W2197903979 cites W1822950385 @default.
- W2197903979 cites W185597165 @default.
- W2197903979 cites W1881509706 @default.
- W2197903979 cites W1933443717 @default.
- W2197903979 cites W1941198163 @default.
- W2197903979 cites W1944616574 @default.
- W2197903979 cites W1963489583 @default.
- W2197903979 cites W1963531890 @default.
- W2197903979 cites W1964147298 @default.
- W2197903979 cites W1967659382 @default.
- W2197903979 cites W1969457097 @default.
- W2197903979 cites W1972627435 @default.
- W2197903979 cites W1973553227 @default.
- W2197903979 cites W1975826540 @default.
- W2197903979 cites W1979529504 @default.
- W2197903979 cites W1979920985 @default.
- W2197903979 cites W1986583114 @default.
- W2197903979 cites W1989704213 @default.
- W2197903979 cites W1991129198 @default.
- W2197903979 cites W1992969897 @default.
- W2197903979 cites W1995375941 @default.
- W2197903979 cites W1997559287 @default.
- W2197903979 cites W2000315885 @default.
- W2197903979 cites W2003781437 @default.
- W2197903979 cites W2005159047 @default.
- W2197903979 cites W2005268711 @default.
- W2197903979 cites W2005551571 @default.
- W2197903979 cites W2005782025 @default.
- W2197903979 cites W2009711176 @default.
- W2197903979 cites W2011739365 @default.
- W2197903979 cites W2014061833 @default.
- W2197903979 cites W2014537765 @default.
- W2197903979 cites W2016725641 @default.
- W2197903979 cites W2022349237 @default.
- W2197903979 cites W2027401155 @default.
- W2197903979 cites W2027507003 @default.
- W2197903979 cites W2028502696 @default.
- W2197903979 cites W2028955859 @default.
- W2197903979 cites W2043470737 @default.
- W2197903979 cites W2043720632 @default.
- W2197903979 cites W2047156262 @default.
- W2197903979 cites W2048257867 @default.
- W2197903979 cites W2048962061 @default.
- W2197903979 cites W2049730221 @default.
- W2197903979 cites W2052024448 @default.
- W2197903979 cites W2052978178 @default.
- W2197903979 cites W2055585370 @default.
- W2197903979 cites W2057486293 @default.
- W2197903979 cites W2061632631 @default.
- W2197903979 cites W2062256984 @default.
- W2197903979 cites W2063066707 @default.
- W2197903979 cites W2066730552 @default.
- W2197903979 cites W2066792923 @default.
- W2197903979 cites W2066819715 @default.
- W2197903979 cites W2067977673 @default.
- W2197903979 cites W2070177030 @default.
- W2197903979 cites W2075126357 @default.
- W2197903979 cites W2075598571 @default.
- W2197903979 cites W2076694998 @default.
- W2197903979 cites W2076791201 @default.
- W2197903979 cites W2078840077 @default.
- W2197903979 cites W2079267688 @default.
- W2197903979 cites W2079999639 @default.
- W2197903979 cites W2081690819 @default.
- W2197903979 cites W2082589958 @default.
- W2197903979 cites W2083132416 @default.
- W2197903979 cites W2083173522 @default.
- W2197903979 cites W2085462870 @default.
- W2197903979 cites W208621503 @default.
- W2197903979 cites W2086755326 @default.
- W2197903979 cites W2092590272 @default.
- W2197903979 cites W2093638335 @default.
- W2197903979 cites W2094139594 @default.
- W2197903979 cites W2098293050 @default.
- W2197903979 cites W2098738631 @default.
- W2197903979 cites W2100084977 @default.
- W2197903979 cites W2101545812 @default.
- W2197903979 cites W2105527010 @default.
- W2197903979 cites W2106810444 @default.
- W2197903979 cites W2108096133 @default.
- W2197903979 cites W2117213772 @default.
- W2197903979 cites W2118548680 @default.
- W2197903979 cites W2118898409 @default.
- W2197903979 cites W2120618997 @default.
- W2197903979 cites W2122910319 @default.
- W2197903979 cites W2125375257 @default.
- W2197903979 cites W2127860870 @default.
- W2197903979 cites W2142202531 @default.