Matches in SemOpenAlex for { <https://semopenalex.org/work/W2197906164> ?p ?o ?g. }
- W2197906164 endingPage "C336" @default.
- W2197906164 startingPage "C328" @default.
- W2197906164 abstract "The K+ channel of HeLa S3 cells in metaphase was analyzed by inside-out and whole cell patch-clamp techniques. The channel had the characteristics of strong inward rectification, small conductance (22 pS at -100 mV), and dependence on intracellular Ca2+. We investigated the cell cycle dependency of the channel, using cells synchronized by harvesting them at the mitotic stage. The cell capacitance increased gradually with increases in the cell volume toward the S phase. The inward K+ currents through the channel at fixed membrane potentials were highest in early G1 and then decreased with time to a minimum in the S phase, increasing again in the M phase. The permeabilities at fixed membrane potentials were also highest in early G1, decreased to minima in the S phase, and increased again toward the next mitosis. In contrast, mean amplitude and the open probability of the single channel at a fixed membrane potential (-60 mV) did not change significantly during the cell cycle. Therefore the capacitance increases with progression of the cell cycle, whereas the permeability decreases from early G1 to an apparent minimum in the S phase. These changes may be caused by cell cycle-dependent changes in the number of channels." @default.
- W2197906164 created "2016-06-24" @default.
- W2197906164 creator A5008767253 @default.
- W2197906164 creator A5040748885 @default.
- W2197906164 creator A5090795865 @default.
- W2197906164 date "1993-08-01" @default.
- W2197906164 modified "2023-10-16" @default.
- W2197906164 title "Change in K+ current of HeLa cells with progression of the cell cycle studied by patch-clamp technique" @default.
- W2197906164 cites W1532963768 @default.
- W2197906164 cites W1976810053 @default.
- W2197906164 cites W1977187673 @default.
- W2197906164 cites W1979418164 @default.
- W2197906164 cites W1986887981 @default.
- W2197906164 cites W1992532194 @default.
- W2197906164 cites W2006948669 @default.
- W2197906164 cites W2009667219 @default.
- W2197906164 cites W2011341369 @default.
- W2197906164 cites W2012516152 @default.
- W2197906164 cites W2016554763 @default.
- W2197906164 cites W2020857462 @default.
- W2197906164 cites W2025376998 @default.
- W2197906164 cites W2031879983 @default.
- W2197906164 cites W2042178762 @default.
- W2197906164 cites W2042760229 @default.
- W2197906164 cites W2055188285 @default.
- W2197906164 cites W2066309047 @default.
- W2197906164 cites W2084321750 @default.
- W2197906164 cites W2087696801 @default.
- W2197906164 cites W2088233139 @default.
- W2197906164 cites W2089269712 @default.
- W2197906164 cites W2093182768 @default.
- W2197906164 cites W2119878219 @default.
- W2197906164 cites W2120772267 @default.
- W2197906164 cites W2140018115 @default.
- W2197906164 cites W2141647137 @default.
- W2197906164 cites W2145612049 @default.
- W2197906164 cites W2156225549 @default.
- W2197906164 doi "https://doi.org/10.1152/ajpcell.1993.265.2.c328" @default.
- W2197906164 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8368262" @default.
- W2197906164 hasPublicationYear "1993" @default.
- W2197906164 type Work @default.
- W2197906164 sameAs 2197906164 @default.
- W2197906164 citedByCount "40" @default.
- W2197906164 countsByYear W21979061642013 @default.
- W2197906164 countsByYear W21979061642014 @default.
- W2197906164 countsByYear W21979061642020 @default.
- W2197906164 countsByYear W21979061642021 @default.
- W2197906164 countsByYear W21979061642022 @default.
- W2197906164 countsByYear W21979061642023 @default.
- W2197906164 crossrefType "journal-article" @default.
- W2197906164 hasAuthorship W2197906164A5008767253 @default.
- W2197906164 hasAuthorship W2197906164A5040748885 @default.
- W2197906164 hasAuthorship W2197906164A5090795865 @default.
- W2197906164 hasConcept C104317684 @default.
- W2197906164 hasConcept C121332964 @default.
- W2197906164 hasConcept C121932024 @default.
- W2197906164 hasConcept C12554922 @default.
- W2197906164 hasConcept C147944092 @default.
- W2197906164 hasConcept C1491633281 @default.
- W2197906164 hasConcept C169760540 @default.
- W2197906164 hasConcept C181911157 @default.
- W2197906164 hasConcept C185263204 @default.
- W2197906164 hasConcept C185592680 @default.
- W2197906164 hasConcept C192562407 @default.
- W2197906164 hasConcept C26873012 @default.
- W2197906164 hasConcept C2777366897 @default.
- W2197906164 hasConcept C29537977 @default.
- W2197906164 hasConcept C30481170 @default.
- W2197906164 hasConcept C55493867 @default.
- W2197906164 hasConcept C70278784 @default.
- W2197906164 hasConcept C79879829 @default.
- W2197906164 hasConcept C86803240 @default.
- W2197906164 hasConcept C93304396 @default.
- W2197906164 hasConcept C95444343 @default.
- W2197906164 hasConceptScore W2197906164C104317684 @default.
- W2197906164 hasConceptScore W2197906164C121332964 @default.
- W2197906164 hasConceptScore W2197906164C121932024 @default.
- W2197906164 hasConceptScore W2197906164C12554922 @default.
- W2197906164 hasConceptScore W2197906164C147944092 @default.
- W2197906164 hasConceptScore W2197906164C1491633281 @default.
- W2197906164 hasConceptScore W2197906164C169760540 @default.
- W2197906164 hasConceptScore W2197906164C181911157 @default.
- W2197906164 hasConceptScore W2197906164C185263204 @default.
- W2197906164 hasConceptScore W2197906164C185592680 @default.
- W2197906164 hasConceptScore W2197906164C192562407 @default.
- W2197906164 hasConceptScore W2197906164C26873012 @default.
- W2197906164 hasConceptScore W2197906164C2777366897 @default.
- W2197906164 hasConceptScore W2197906164C29537977 @default.
- W2197906164 hasConceptScore W2197906164C30481170 @default.
- W2197906164 hasConceptScore W2197906164C55493867 @default.
- W2197906164 hasConceptScore W2197906164C70278784 @default.
- W2197906164 hasConceptScore W2197906164C79879829 @default.
- W2197906164 hasConceptScore W2197906164C86803240 @default.
- W2197906164 hasConceptScore W2197906164C93304396 @default.
- W2197906164 hasConceptScore W2197906164C95444343 @default.
- W2197906164 hasIssue "2" @default.
- W2197906164 hasLocation W21979061641 @default.
- W2197906164 hasLocation W21979061642 @default.