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• W2198142008 abstract "Abstract Plant biotechnology offers us the ability to augment and improve upon biological systems to produce value added crops, medicines, or specialized products. The application of cyclotides, either naturally occurring or engineered, requires their production at industrial-scale yields. Here we discuss the most relevant applications of cyclotides within a plant biotechnological context and present biological, regulatory, and market factors that should be considered when embarking on a cyclotide production project in planta. It is evident that only a select few plants appear to have evolved to produce cyclotides, as introduced in Chapters 1–4 Chapter 1 Chapter 2 Chapter 3 Chapter 4 , where they putatively function as highly abundant defense molecules. Their high abundance and stability suggest that they are of primary importance to the species that contain them. Plant biotechnology could be used to harness this functionality and to engineer novel designer cyclotides for expression in plants. We finish with a brief discussion of what the future may hold for cyclotide-based biotechnology." @default.
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• W2198142008 date "2015-01-01" @default.
• W2198142008 modified "2023-10-13" @default.
• W2198142008 title "Cyclotides in a Biotechnological Context" @default.
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• W2198142008 doi "https://doi.org/10.1016/bs.abr.2015.09.010" @default.
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