FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2198914713> ?p ?o ?g. }

• W2198914713 endingPage "202" @default.
• W2198914713 startingPage "192" @default.
• W2198914713 abstract "Background Ultraviolet radiation (UVR) and crude coal tar (CCT) containing PAHs can accelerate the skin-aging process (SAP). However, UVR induces the formation of an important protective factor in SAP (vitamin D). Objective To determine the relation of SAP to selected risks and benefits of combined dermal exposure to UVR and coal tar (PAHs). Methods The study group consisted of patients with chronic stable plaque psoriasis and treated by Goeckerman therapy (GT; daily dermal application of UVR and 5% CCT ointment). The levels of urinary 1-hydroxypyrene (1-OHP), oxidative stress (DNA and RNA damage), genotoxic damage (chromosomal aberration in peripheral lymphocytes; ABC), 25-hydroxy-vitamin D [25(OH)D] and the PASI score were evaluated before and after GT. Results Intensive dermal absorption of PAHs was confirmed by increased levels of 1-OHP (p < 0.01). After the therapy, we found an increased level of oxidative stress (p < 0.05), an increased level of genotoxic damage (ABC; p < 0.001), a high efficiency of the treatment (p < 0.001) and an elevated production of 25(OH)D (p < 0.01). We also found a relationship between the duration of UVR and the genotoxic damage (p < 0.01), vitD (p < 0.05) and the PASI score (p < 0.05). Furthermore, we found a relationship between oxidative stress and 25(OH)D (p < 0.05) and between genotoxic damage and the PASI score (p < 0.05). Conclusion Dermal exposure to UVR and coal tar (PAHs) enhances the level of oxidative stress and genotoxic damage and thus contributes to SAP. However, the exposure is very effective as a treatment and elevates the production of 25(OH)D, the protective factor in SAP. According to our results, UVR is probably a more hazardous factor in SAP." @default.
• W2198914713 created "2016-06-24" @default.
• W2198914713 creator A5037945092 @default.
• W2198914713 creator A5042505182 @default.
• W2198914713 creator A5044377567 @default.
• W2198914713 creator A5044528968 @default.
• W2198914713 creator A5050623525 @default.
• W2198914713 creator A5051132310 @default.
• W2198914713 creator A5068049867 @default.
• W2198914713 creator A5072684109 @default.
• W2198914713 creator A5081337241 @default.
• W2198914713 date "2016-03-01" @default.
• W2198914713 modified "2023-10-16" @default.
• W2198914713 title "Influence of dermal exposure to ultraviolet radiation and coal tar (polycyclic aromatic hydrocarbons) on the skin aging process" @default.
• W2198914713 cites W1907107933 @default.
• W2198914713 cites W1924915641 @default.
• W2198914713 cites W1966985887 @default.
• W2198914713 cites W1970124511 @default.
• W2198914713 cites W1972763155 @default.
• W2198914713 cites W1976619282 @default.
• W2198914713 cites W1976840481 @default.
• W2198914713 cites W1978714791 @default.
• W2198914713 cites W1979030206 @default.
• W2198914713 cites W1982775535 @default.
• W2198914713 cites W1985087138 @default.
• W2198914713 cites W1997615085 @default.
• W2198914713 cites W1999074937 @default.
• W2198914713 cites W2002353175 @default.
• W2198914713 cites W2005794877 @default.
• W2198914713 cites W2007113704 @default.
• W2198914713 cites W2018427304 @default.
• W2198914713 cites W2018929224 @default.
• W2198914713 cites W2021018799 @default.
• W2198914713 cites W2025638533 @default.
• W2198914713 cites W2025727364 @default.
• W2198914713 cites W2040796648 @default.
• W2198914713 cites W2042396570 @default.
• W2198914713 cites W2048521153 @default.
• W2198914713 cites W2049755715 @default.
• W2198914713 cites W2053366385 @default.
• W2198914713 cites W2053491009 @default.
• W2198914713 cites W2054546084 @default.
• W2198914713 cites W2067251767 @default.
• W2198914713 cites W2070631544 @default.
• W2198914713 cites W2073223435 @default.
• W2198914713 cites W2074503352 @default.
• W2198914713 cites W2076150848 @default.
• W2198914713 cites W2077124774 @default.
• W2198914713 cites W2083289190 @default.
• W2198914713 cites W2088155302 @default.
• W2198914713 cites W2088221629 @default.
• W2198914713 cites W2089630017 @default.
• W2198914713 cites W2091573033 @default.
• W2198914713 cites W2092567285 @default.
• W2198914713 cites W2105555619 @default.
• W2198914713 cites W2110704362 @default.
• W2198914713 cites W2112110686 @default.
• W2198914713 cites W2119307913 @default.
• W2198914713 cites W2124725201 @default.
• W2198914713 cites W2124911828 @default.
• W2198914713 cites W2129943496 @default.
• W2198914713 cites W2131643175 @default.
• W2198914713 cites W2136740663 @default.
• W2198914713 cites W2140941758 @default.
• W2198914713 cites W2142876469 @default.
• W2198914713 cites W2144426362 @default.
• W2198914713 cites W2164123176 @default.
• W2198914713 cites W2328839710 @default.
• W2198914713 cites W2762467853 @default.
• W2198914713 doi "https://doi.org/10.1016/j.jdermsci.2015.12.010" @default.
• W2198914713 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26748978" @default.
• W2198914713 hasPublicationYear "2016" @default.
• W2198914713 type Work @default.
• W2198914713 sameAs 2198914713 @default.
• W2198914713 citedByCount "18" @default.
• W2198914713 countsByYear W21989147132016 @default.
• W2198914713 countsByYear W21989147132017 @default.
• W2198914713 countsByYear W21989147132019 @default.
• W2198914713 countsByYear W21989147132020 @default.
• W2198914713 countsByYear W21989147132021 @default.
• W2198914713 countsByYear W21989147132022 @default.
• W2198914713 countsByYear W21989147132023 @default.
• W2198914713 crossrefType "journal-article" @default.
• W2198914713 hasAuthorship W2198914713A5037945092 @default.
• W2198914713 hasAuthorship W2198914713A5042505182 @default.
• W2198914713 hasAuthorship W2198914713A5044377567 @default.
• W2198914713 hasAuthorship W2198914713A5044528968 @default.
• W2198914713 hasAuthorship W2198914713A5050623525 @default.
• W2198914713 hasAuthorship W2198914713A5051132310 @default.
• W2198914713 hasAuthorship W2198914713A5068049867 @default.
• W2198914713 hasAuthorship W2198914713A5072684109 @default.
• W2198914713 hasAuthorship W2198914713A5081337241 @default.
• W2198914713 hasConcept C143425029 @default.
• W2198914713 hasConcept C178790620 @default.
• W2198914713 hasConcept C185592680 @default.
• W2198914713 hasConcept C192643346 @default.
• W2198914713 hasConcept C199360897 @default.
• W2198914713 hasConcept C2776151105 @default.

• next