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• W2199547434 abstract "Abstract Objective To assess the efficacy of triclabendazole (TCBZ) in porcine cysticercosis. Methods Eighteen naturally infected cysticercosis pigs were divided into 3 groups of 6 individuals each. The first group was treated orally with TCBZ at a single dose of 30 mg/kg of body weight, the second group was treated orally with oxfendazole at a single dose of 30 mg/kg of body weight and the third group received a placebo (control group). All animals were kept under the same management conditions. The pigs were euthanized 17 wk post-treatment and the number of surviving cysts in muscles was assessed and compared between groups. Results All pigs treated with oxfendazole had only degenerated cysts in their carcasses. In contrast, TCBZ had very little effect against the parasitic cysts. Cysts from pigs in the TCBZ group looked apparently normal after treatment. However, histological evaluation showed a mild to moderate degree of inflammation. Conclusions TCBZ is not an efficacious drug against Taenia solium cysticercosis in swine using a single dose." @default.
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• W2199547434 date "2016-01-01" @default.
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• W2199547434 title "Evaluation of activity of triclabendazole against Taenia solium metacestode in naturally infected pigs" @default.
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• W2199547434 doi "https://doi.org/10.1016/j.apjtm.2015.12.005" @default.
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