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- W2199620791 abstract "Streptococcus pneumoniae is a leading cause of illness and death in adults. A polysaccharide vaccine has been available for over 30 years, but despite significant use, the public health impact of this vaccine has been limited. The 13-valent pneumococcal conjugate vaccine (PCV13) has been licensed by the US Food and Drug Administration and other international regulatory authorities with the assumption that induction of a T cell–dependent immune response and noninferior immunogenicity to vaccine antigens when compared with the polysaccharide vaccine would be important to satisfy a significant unmet medical need. PCV13 efficacy against vaccine-type pneumococcal community-acquired pneumonia was confirmed in a large randomized controlled trial in older adults and its use is now increasingly recommended globally." @default.
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- W2199620791 date "2015-12-29" @default.
- W2199620791 modified "2023-10-18" @default.
- W2199620791 title "Pneumococcal conjugate vaccine use in adults" @default.
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- W2199620791 doi "https://doi.org/10.1586/14760584.2016.1132171" @default.
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