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• W2200140377 endingPage "166" @default.
• W2200140377 startingPage "126" @default.
• W2200140377 abstract "Fungi do not have different sexes characterized by specific morphological organs but control sexual development by physiological differences defined by mating types. While other lineages in the fungal kingdom have only two distinct mating types, multiple mating types are common in the Basidiomycetes, presumably for outcomes related to enhanced outbreeding. Mating types in Basidiomycetes are determined by genes that encode two types of homeodomain transcription factors (HD genes) and by genes that encode lipopeptide pheromones and pheromone receptors (PR genes). In the tetrapolar mushroom Coprinopsis cinerea, these genes reside at two distinct loci on different chromosomes and regulate distinct steps in dikaryon formation and maintenance and fruiting body formation for sexual reproduction by controlling the expression of large sets of genes. The matA (HD) locus in C. cinerea has an estimated 160 alleles in nature, and the matB (PR) locus has 79. The respective products of both loci interact with each other in a lock-and-key manner. Proteins encoded in allelic sets of mating type genes recognize each other and interact in order to either form a functional transcription factor complex that is transported into the nucleus (matA proteins) or to initiate a pheromone response signaling cascade (matB proteins). Products encoded by the same matA or matB allele do not interact, which is crucial to the functionality of the two systems controlling sexual development. Multiple alleles of mating type genes arose in evolution through the evolution of distinct DNA sequences and the resulting encoded proteins perform the tasks of recognition and discrimination. In a second modus of multiplication, paralogous sets of HD and PR genes evolved by gene duplications and subsequent sequence diversification in order to mediate functional independency and respective allele variation. In C. cinerea, there are thus three paralogous groups of functional mating type genes at both the matA and the matB locus. Because groups of paralogous genes are freely interchangeable, only a few alleles of each of the actual gene groups (between 2 and 9 are known per group) are required to generate the large number of distinct matA and matB mating types found in nature. As deduced from the ever increasing number of genome projects, the basic principles of evolution of multiple mating types as unraveled in C. cinerea by Lorna A. Casselton and her coworkers are to different degrees also operative in other mushroom species." @default.
• W2200140377 created "2016-06-24" @default.
• W2200140377 creator A5030126992 @default.
• W2200140377 date "2015-12-01" @default.
• W2200140377 modified "2023-10-16" @default.
• W2200140377 title "From two to many: Multiple mating types in Basidiomycetes" @default.
• W2200140377 cites W1019532447 @default.
• W2200140377 cites W1209142595 @default.
• W2200140377 cites W1246975646 @default.
• W2200140377 cites W1250825572 @default.
• W2200140377 cites W1483845992 @default.
• W2200140377 cites W1491112128 @default.
• W2200140377 cites W1519674894 @default.
• W2200140377 cites W1536106618 @default.
• W2200140377 cites W1547548607 @default.
• W2200140377 cites W1570067302 @default.
• W2200140377 cites W160800102 @default.
• W2200140377 cites W163632947 @default.
• W2200140377 cites W167771405 @default.
• W2200140377 cites W1797452114 @default.
• W2200140377 cites W180204247 @default.
• W2200140377 cites W1820552278 @default.
• W2200140377 cites W1833422288 @default.
• W2200140377 cites W1838456182 @default.
• W2200140377 cites W1859619881 @default.
• W2200140377 cites W1860018264 @default.
• W2200140377 cites W1869253992 @default.
• W2200140377 cites W1886625688 @default.
• W2200140377 cites W1905931650 @default.
• W2200140377 cites W1909567899 @default.
• W2200140377 cites W1917798260 @default.
• W2200140377 cites W1937262478 @default.
• W2200140377 cites W1945784894 @default.
• W2200140377 cites W1949027200 @default.
• W2200140377 cites W1952168368 @default.
• W2200140377 cites W1960000138 @default.
• W2200140377 cites W1961177618 @default.
• W2200140377 cites W1962512836 @default.
• W2200140377 cites W1963616774 @default.
• W2200140377 cites W1964128867 @default.
• W2200140377 cites W1964501245 @default.
• W2200140377 cites W1965169597 @default.
• W2200140377 cites W1965581246 @default.
• W2200140377 cites W1965611938 @default.
• W2200140377 cites W1965700497 @default.
• W2200140377 cites W1966772876 @default.
• W2200140377 cites W1969369802 @default.
• W2200140377 cites W1969900439 @default.
• W2200140377 cites W1970218657 @default.
• W2200140377 cites W1971816018 @default.
• W2200140377 cites W1973235966 @default.
• W2200140377 cites W1974233121 @default.
• W2200140377 cites W1974360015 @default.
• W2200140377 cites W1974901081 @default.
• W2200140377 cites W1975093867 @default.
• W2200140377 cites W1976234046 @default.
• W2200140377 cites W1977509789 @default.
• W2200140377 cites W1978677176 @default.
• W2200140377 cites W1978816187 @default.
• W2200140377 cites W1979125992 @default.
• W2200140377 cites W1979339691 @default.
• W2200140377 cites W1979551779 @default.
• W2200140377 cites W1979563149 @default.
• W2200140377 cites W1979603047 @default.
• W2200140377 cites W1980587229 @default.
• W2200140377 cites W1981214985 @default.
• W2200140377 cites W1981301001 @default.
• W2200140377 cites W1982390665 @default.
• W2200140377 cites W1982493459 @default.
• W2200140377 cites W1983511720 @default.
• W2200140377 cites W1984177909 @default.
• W2200140377 cites W1984519423 @default.
• W2200140377 cites W1985837667 @default.
• W2200140377 cites W1986678432 @default.
• W2200140377 cites W1986856892 @default.
• W2200140377 cites W1988011731 @default.
• W2200140377 cites W1989535966 @default.
• W2200140377 cites W1989969748 @default.
• W2200140377 cites W1990761413 @default.
• W2200140377 cites W1991711342 @default.
• W2200140377 cites W1992247485 @default.
• W2200140377 cites W1993385814 @default.
• W2200140377 cites W1994394909 @default.
• W2200140377 cites W1994784578 @default.
• W2200140377 cites W1994872435 @default.
• W2200140377 cites W1997122097 @default.
• W2200140377 cites W1997144691 @default.
• W2200140377 cites W1999358555 @default.
• W2200140377 cites W1999489594 @default.
• W2200140377 cites W1999553924 @default.
• W2200140377 cites W2001311747 @default.
• W2200140377 cites W2001715138 @default.
• W2200140377 cites W2002710273 @default.
• W2200140377 cites W2003079967 @default.
• W2200140377 cites W2005115290 @default.
• W2200140377 cites W2005990654 @default.
• W2200140377 cites W2007358260 @default.
• W2200140377 cites W2008943739 @default.

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