FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2200366188> ?p ?o ?g. }

• W2200366188 endingPage "e85" @default.
• W2200366188 startingPage "e82" @default.
• W2200366188 abstract "The effect of taxanes-based induction chemotherapy (IC) in locoregionally advanced nasopharyngeal carcinoma (LA-NPC) was quite contradictory in two phase II randomized controlled trials with small sample size. We aimed to investigate it in this large scale propensity-matched study.Totally, 779 LA-NPC patients who underwent intensity-modulated radiotherapy (IMRT) plus concurrent chemotherapy with or without taxanes-based IC were included. Patients in both treatment arms were matched using propensity score matching method at the ratio of 1:1. Failure-free survival (FFS), overall survival (OS), distant metastasis-free survival (DMFS) and locoregional relapse-free survival (LRFS) were assessed with Kaplan–Meier method, log-rank test and Cox regression analysis.After matching, 534 patients were identified for analysis. In univariate analysis, both treatment arms resulted in parallel survival (4-years FFS 78.0% vs 74.1%, P = 0.304; OS 87.5% vs 87.3%, P = 0.595; DMFS 88.2% vs 84.4%, P = 0.154; and LRFS 91.2% vs 90.1%, P = 0.960). In multivariate analysis, taxanes-based IC did not improve any survival (P ⩾ 0.139). And this association remained unchanged in subgroup analysis by age, sex and histology, and among patients with stage III and T4N0M0. But among patients with T4N1-2M0 and stage IVb, taxanes-based IC significantly prolonged the 4-year DMFS by 11.2% (86.1% vs 74.9%, P = 0.034), and marginally improved FFS (P = 0.133) and OS (P = 0.215) in both univariate and multivariate analysis.In this large scale propensity-matched study, LA-NPC patients could not benefit from taxanes-based IC on the whole. But the risk of distant metastasis significantly decreased by above 10% for patients with T4N1-2M0 and stage IVb." @default.
• W2200366188 created "2016-06-24" @default.
• W2200366188 creator A5009261802 @default.
• W2200366188 creator A5019980576 @default.
• W2200366188 creator A5041803511 @default.
• W2200366188 creator A5047708663 @default.
• W2200366188 creator A5051746981 @default.
• W2200366188 creator A5079276270 @default.
• W2200366188 creator A5089172550 @default.
• W2200366188 date "2015-11-01" @default.
• W2200366188 modified "2023-09-26" @default.
• W2200366188 title "The time interval between primary surgery and adjuvant therapy determines prognosis of oral squamous cell carcinomas" @default.
• W2200366188 cites W1972246444 @default.
• W2200366188 cites W1985213644 @default.
• W2200366188 cites W1985421003 @default.
• W2200366188 cites W1986705681 @default.
• W2200366188 cites W1987029158 @default.
• W2200366188 cites W2009785294 @default.
• W2200366188 cites W2019051838 @default.
• W2200366188 cites W2038981426 @default.
• W2200366188 cites W2040221084 @default.
• W2200366188 cites W2046453881 @default.
• W2200366188 cites W2051704910 @default.
• W2200366188 cites W2069220645 @default.
• W2200366188 cites W2075225356 @default.
• W2200366188 cites W2098409133 @default.
• W2200366188 cites W2115098571 @default.
• W2200366188 cites W2146934995 @default.
• W2200366188 cites W2165292019 @default.
• W2200366188 cites W2171713829 @default.
• W2200366188 cites W2911964244 @default.
• W2200366188 cites W3099478002 @default.
• W2200366188 doi "https://doi.org/10.1016/j.oraloncology.2015.08.016" @default.
• W2200366188 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26391506" @default.
• W2200366188 hasPublicationYear "2015" @default.
• W2200366188 type Work @default.
• W2200366188 sameAs 2200366188 @default.
• W2200366188 citedByCount "4" @default.
• W2200366188 countsByYear W22003661882016 @default.
• W2200366188 countsByYear W22003661882017 @default.
• W2200366188 countsByYear W22003661882022 @default.
• W2200366188 countsByYear W22003661882023 @default.
• W2200366188 crossrefType "journal-article" @default.
• W2200366188 hasAuthorship W2200366188A5009261802 @default.
• W2200366188 hasAuthorship W2200366188A5019980576 @default.
• W2200366188 hasAuthorship W2200366188A5041803511 @default.
• W2200366188 hasAuthorship W2200366188A5047708663 @default.
• W2200366188 hasAuthorship W2200366188A5051746981 @default.
• W2200366188 hasAuthorship W2200366188A5079276270 @default.
• W2200366188 hasAuthorship W2200366188A5089172550 @default.
• W2200366188 hasConcept C10515644 @default.
• W2200366188 hasConcept C126322002 @default.
• W2200366188 hasConcept C143998085 @default.
• W2200366188 hasConcept C144301174 @default.
• W2200366188 hasConcept C146357865 @default.
• W2200366188 hasConcept C151730666 @default.
• W2200366188 hasConcept C17923572 @default.
• W2200366188 hasConcept C187960798 @default.
• W2200366188 hasConcept C2776694085 @default.
• W2200366188 hasConcept C38180746 @default.
• W2200366188 hasConcept C44249647 @default.
• W2200366188 hasConcept C50382708 @default.
• W2200366188 hasConcept C509974204 @default.
• W2200366188 hasConcept C71924100 @default.
• W2200366188 hasConcept C86803240 @default.
• W2200366188 hasConcept C90924648 @default.
• W2200366188 hasConceptScore W2200366188C10515644 @default.
• W2200366188 hasConceptScore W2200366188C126322002 @default.
• W2200366188 hasConceptScore W2200366188C143998085 @default.
• W2200366188 hasConceptScore W2200366188C144301174 @default.
• W2200366188 hasConceptScore W2200366188C146357865 @default.
• W2200366188 hasConceptScore W2200366188C151730666 @default.
• W2200366188 hasConceptScore W2200366188C17923572 @default.
• W2200366188 hasConceptScore W2200366188C187960798 @default.
• W2200366188 hasConceptScore W2200366188C2776694085 @default.
• W2200366188 hasConceptScore W2200366188C38180746 @default.
• W2200366188 hasConceptScore W2200366188C44249647 @default.
• W2200366188 hasConceptScore W2200366188C50382708 @default.
• W2200366188 hasConceptScore W2200366188C509974204 @default.
• W2200366188 hasConceptScore W2200366188C71924100 @default.
• W2200366188 hasConceptScore W2200366188C86803240 @default.
• W2200366188 hasConceptScore W2200366188C90924648 @default.
• W2200366188 hasIssue "11" @default.
• W2200366188 hasLocation W22003661881 @default.
• W2200366188 hasLocation W22003661882 @default.
• W2200366188 hasOpenAccess W2200366188 @default.
• W2200366188 hasPrimaryLocation W22003661881 @default.
• W2200366188 hasRelatedWork W2361700749 @default.
• W2200366188 hasRelatedWork W2361948491 @default.
• W2200366188 hasRelatedWork W2375386244 @default.
• W2200366188 hasRelatedWork W2375813207 @default.
• W2200366188 hasRelatedWork W2376752247 @default.
• W2200366188 hasRelatedWork W2389549616 @default.
• W2200366188 hasRelatedWork W3083506315 @default.
• W2200366188 hasRelatedWork W4238506989 @default.
• W2200366188 hasRelatedWork W4245990988 @default.
• W2200366188 hasRelatedWork W1951105103 @default.
• W2200366188 hasVolume "51" @default.

• next