FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2200516948> ?p ?o ?g. }

• W2200516948 endingPage "1736" @default.
• W2200516948 startingPage "1731" @default.
• W2200516948 abstract "Background Parameningeal rhabdomyosarcomas (PM‐RMSs) represent approximately 25% of all rhabdomyosarcoma (RMS) cases. These tumors are associated with early recurrence and poor prognosis. This study assessed the clinical outcome and late toxicity of pencil beam scanning (PBS) proton therapy (PT) in the treatment of children with PM‐RMS. Procedures Thirty‐nine children with PM‐RMS received neoadjuvant chemotherapy followed by PBS‐PT at the Paul Scherrer Institute, with concomitant chemotherapy. The median age was 5.8 years (range, 1.2–16.1). Due to young age, 25 patients (64%) required general anesthesia during PT. The median time from the start of chemotherapy to PT was 13 weeks (range, 3–23 weeks). Median prescription dose was 54 Gy (relative biologic effectiveness, RBE). Results With a mean follow‐up of 41 months (range, 9–106 months), 10 patients failed. The actuarial 5‐year progression‐free survival (PFS) was 72% (95% CI, 67–94%) and the 5‐year overall survival was 73% (95% CI, 69–96%). On univariate analysis, a delay in the initiation of PT (>13 weeks) was a significant detrimental factor for PFS. Three (8%) patients presented with grade 3 radiation‐induced toxicity. The estimated actuarial 5‐year toxicity ≥grade 3 free survival was 95% (95% CI, 94–96%). Conclusions Our data contribute to the growing body of evidence demonstrating the safety and effectiveness of PT for pediatric patients with PM‐RMS. These preliminary results are encouraging and in line with other combined proton–photon and photons series; observed toxicity was acceptable." @default.
• W2200516948 created "2016-06-24" @default.
• W2200516948 creator A5017607013 @default.
• W2200516948 creator A5035870007 @default.
• W2200516948 creator A5038604161 @default.
• W2200516948 creator A5042084730 @default.
• W2200516948 creator A5059888019 @default.
• W2200516948 creator A5060976792 @default.
• W2200516948 creator A5064668846 @default.
• W2200516948 date "2015-12-23" @default.
• W2200516948 modified "2023-10-16" @default.
• W2200516948 title "Pencil Beam Scanning Proton Therapy for Pediatric Parameningeal Rhabdomyosarcomas: Clinical Outcome of Patients Treated at the Paul Scherrer Institute" @default.
• W2200516948 cites W106479914 @default.
• W2200516948 cites W1427575489 @default.
• W2200516948 cites W1693048258 @default.
• W2200516948 cites W1926287352 @default.
• W2200516948 cites W1965812821 @default.
• W2200516948 cites W1970934200 @default.
• W2200516948 cites W1979045673 @default.
• W2200516948 cites W1983042789 @default.
• W2200516948 cites W1984504326 @default.
• W2200516948 cites W1990026881 @default.
• W2200516948 cites W2012810905 @default.
• W2200516948 cites W2028165537 @default.
• W2200516948 cites W202938842 @default.
• W2200516948 cites W2035306925 @default.
• W2200516948 cites W2040855744 @default.
• W2200516948 cites W2044095878 @default.
• W2200516948 cites W2060892396 @default.
• W2200516948 cites W2075833875 @default.
• W2200516948 cites W2077581316 @default.
• W2200516948 cites W2086479790 @default.
• W2200516948 cites W2094591030 @default.
• W2200516948 cites W2094617809 @default.
• W2200516948 cites W2116047364 @default.
• W2200516948 cites W2120060416 @default.
• W2200516948 cites W2137960802 @default.
• W2200516948 cites W2142896727 @default.
• W2200516948 cites W2163218852 @default.
• W2200516948 cites W2170560268 @default.
• W2200516948 doi "https://doi.org/10.1002/pbc.25864" @default.
• W2200516948 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26701148" @default.
• W2200516948 hasPublicationYear "2015" @default.
• W2200516948 type Work @default.
• W2200516948 sameAs 2200516948 @default.
• W2200516948 citedByCount "32" @default.
• W2200516948 countsByYear W22005169482016 @default.
• W2200516948 countsByYear W22005169482017 @default.
• W2200516948 countsByYear W22005169482018 @default.
• W2200516948 countsByYear W22005169482019 @default.
• W2200516948 countsByYear W22005169482020 @default.
• W2200516948 countsByYear W22005169482021 @default.
• W2200516948 countsByYear W22005169482022 @default.
• W2200516948 countsByYear W22005169482023 @default.
• W2200516948 crossrefType "journal-article" @default.
• W2200516948 hasAuthorship W2200516948A5017607013 @default.
• W2200516948 hasAuthorship W2200516948A5035870007 @default.
• W2200516948 hasAuthorship W2200516948A5038604161 @default.
• W2200516948 hasAuthorship W2200516948A5042084730 @default.
• W2200516948 hasAuthorship W2200516948A5059888019 @default.
• W2200516948 hasAuthorship W2200516948A5060976792 @default.
• W2200516948 hasAuthorship W2200516948A5064668846 @default.
• W2200516948 hasConcept C126322002 @default.
• W2200516948 hasConcept C141071460 @default.
• W2200516948 hasConcept C142724271 @default.
• W2200516948 hasConcept C144301174 @default.
• W2200516948 hasConcept C2775881188 @default.
• W2200516948 hasConcept C2776694085 @default.
• W2200516948 hasConcept C2778256501 @default.
• W2200516948 hasConcept C2779244869 @default.
• W2200516948 hasConcept C2779384505 @default.
• W2200516948 hasConcept C2780844630 @default.
• W2200516948 hasConcept C29730261 @default.
• W2200516948 hasConcept C2989005 @default.
• W2200516948 hasConcept C38180746 @default.
• W2200516948 hasConcept C509974204 @default.
• W2200516948 hasConcept C71924100 @default.
• W2200516948 hasConceptScore W2200516948C126322002 @default.
• W2200516948 hasConceptScore W2200516948C141071460 @default.
• W2200516948 hasConceptScore W2200516948C142724271 @default.
• W2200516948 hasConceptScore W2200516948C144301174 @default.
• W2200516948 hasConceptScore W2200516948C2775881188 @default.
• W2200516948 hasConceptScore W2200516948C2776694085 @default.
• W2200516948 hasConceptScore W2200516948C2778256501 @default.
• W2200516948 hasConceptScore W2200516948C2779244869 @default.
• W2200516948 hasConceptScore W2200516948C2779384505 @default.
• W2200516948 hasConceptScore W2200516948C2780844630 @default.
• W2200516948 hasConceptScore W2200516948C29730261 @default.
• W2200516948 hasConceptScore W2200516948C2989005 @default.
• W2200516948 hasConceptScore W2200516948C38180746 @default.
• W2200516948 hasConceptScore W2200516948C509974204 @default.
• W2200516948 hasConceptScore W2200516948C71924100 @default.
• W2200516948 hasIssue "10" @default.
• W2200516948 hasLocation W22005169481 @default.
• W2200516948 hasLocation W22005169482 @default.
• W2200516948 hasOpenAccess W2200516948 @default.
• W2200516948 hasPrimaryLocation W22005169481 @default.
• W2200516948 hasRelatedWork W1989003092 @default.

• next