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- W2200522790 abstract "Publisher Summary This chapter describes the behavioral pharmacology of sleep. The sensitivity of sleep parameters to the effects of psychoactive drugs makes the behavioral pharmacology of EEG and sleep an interesting tool for research of the central nervous system. Major progress has been made in the discovery of nonbenzodiazepine hypnotics with fewer unwanted effects. Twenty years of sleep research has also resulted in a much better understanding of sleep. The two-process model of sleep, with an emphasis on the power of the delta waves as its main parameter, provides a new way of thinking with consequences for the behavioral pharmacology of sleep. The chapter presents a methodological overview of the basic problems and questions in the pharmacology of preclinical sleep research. A behavioral definition of sleep is presented, followed by a definition in terms of electrophysiological parameters. New developments are briefly introduced, which are expected to have major impact on the evaluation of putative hypnotic compounds. The chapter describes different animal models followed by an introduction to the different procedures available to the sleep researcher. It also presents an analysis of some of the critical problems encountered in the behavioral pharmacology of sleep." @default.
- W2200522790 created "2016-06-24" @default.
- W2200522790 creator A5048880890 @default.
- W2200522790 creator A5089659389 @default.
- W2200522790 date "1993-01-01" @default.
- W2200522790 modified "2023-09-27" @default.
- W2200522790 title "The behavioral pharmacology of sleep" @default.
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